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用途
sufficient for 250 colorimetric tests
检测方法
colorimetric
相关疾病
genitourinary disorders; gastrointestinal diseases
储存温度
−20°C
基因信息
human ... ALB(213)
mouse ... ALB(11657)
rat ... ALB(24186)
一般描述
白蛋白是人体中丰度最高的血浆蛋白。它占总血清蛋白质的∼60%。白蛋白具有重要的生理作用，包括维持胶体渗透压，结合长链脂肪酸、胆汁酸、胆红素、血红素、钙、镁等关键物质。它具有抗氧化和抗凝血作用，是营养因子和药物的载体，也是一种有效的血浆pH缓冲液。血清白蛋白是发病率和死亡率、肝病、肾病综合征、营养不良和蛋白质丢失性肠病的可靠预后指标。高水平的白蛋白与脱水有关。
应用
- LncRNA ZEB1-AS1 inhibits renal fibrosis in diabetic nephropathy by regulating the miR-217/MAFB axis.：本文使用BCG法白蛋白测定试剂盒定量分析白蛋白，进行糖尿病肾病研究。结果说明lncRNA调节miR-217/MAFB轴的作用，显著增加糖尿病患者肾纤维化的信息和治疗手段(Song et al., 2019)。
- Albumin depletion of human plasma also removes low abundance proteins including the cytokines.：本文使用BCG法白蛋白测定试剂盒研究人血浆中白蛋白缺失的影响，尤其是对细胞因子等低丰度蛋白的影响。有助于改进蛋白质组学分析，理解生物样本中的蛋白互作(Granger et al., 2005)。
特点和优势
兼容高通量操作系统。经改装可用于试管。
适用性
适用于检测血清、血浆、尿液和其它生物样本中的白蛋白。
原理
BCG（溴甲酚绿）白蛋白检测试剂盒旨在不经样品预处理直接测定白蛋白。优化后的配方可大幅减少原始样品中其他物质（配体/其他蛋白质）的干扰。也可用于测量药物和其他化合物对白蛋白代谢的影响。该过程包括添加单一工作试剂和5分钟的孵育。优化后的配方大大提高了试剂和信号的稳定性。该试剂盒采用溴甲酚绿，与白蛋白形成特殊的彩色复合物。颜色的强度（在620nm处测量）与样品中的白蛋白浓度成正比。
储存分类代码
12 - Non Combustible Liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Maria Callejo et al.
Journal of clinical medicine, 9(2) (2020-02-12)
Introduction: Epidemiological studies suggest a relationship between vitamin D deficiency and cardiovascular and respiratory diseases. However, whether total, bioavailable, and/or free vitamin D levels have a prognostic role in pulmonary arterial hypertension (PAH) is unknown. We aimed to determine total
Marvin Gonzalez-Quiroz et al.
BMC nephrology, 20(1), 21-21 (2019-01-18)
After two-years of follow-up of 263 apparently healthy 18- to 30-year-old men in communities affected by Mesoamerican nephropathy (MeN), we identified three distinct case groups: a subgroup with (i) established renal dysfunction (case-group 1); individuals with (ii) a rapid decline in
Alaa T Alshareeda et al.
PloS one, 12(8), e0184004-e0184004 (2017-08-30)
Hepatocellular carcinoma (HCC) is considered the 3rd leading cause of death by cancer worldwide with the majority of patients were diagnosed in the late stages. Currently, there is no effective therapy. The selection of an animal model that mimics human
Yin-Ting Yeh et al.
Scientific reports, 8(1), 13623-13623 (2018-09-13)
Blood is a complex fluid consisting of cells and plasma. Plasma contains key biomarkers essential for disease diagnosis and therapeutic monitoring. Thus, by separating plasma from the blood, it is possible to analyze these biomarkers. Conventional methods for plasma extraction
Jun Li et al.
Kidney international, 95(3), 611-623 (2019-01-28)
Chronic antibody-mediated rejection is the leading cause of allograft dysfunction and loss after kidney transplantation, and current immunosuppressive regimens fail to target the plasma cells that produce alloantibodies. We previously showed that treatment with the immunoproteasome inhibitor ONX 0914 prevented
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