所有图片(3)
About This Item
经验公式（希尔记法）:
C9H10N2
CAS号:
分子量:
146.19
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
≥98%
表单
solid
储存温度
2-8°C
SMILES字符串
C1CN=C(C1)c2cccnc2
InChI
1S/C9H10N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7H,2,4,6H2
InChI key
DPNGWXJMIILTBS-UHFFFAOYSA-N
基因信息
rat ... Chrna4(25590)
应用
烟碱
用于以下反应的反应物：
亚硝化反应
与过氧化氢的过氧化反应
用于以下反应的反应物：
亚硝化反应
与过氧化氢的过氧化反应
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Katharina Schütte-Borkovec et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 14(5), 278-284 (2009-05-30)
Myosmine is a minor tobacco alkaloid with widespread occurrence in the human diet. Myosmine is genotoxic in human cells and is readily nitrosated and peroxidated yielding reactive intermediates with carcinogenic potential. For biomonitoring of short-term and long-term exposure, analytical methods
W Zwickenpflug
Journal of agricultural and food chemistry, 48(2), 392-394 (2000-02-26)
N-Nitrosonornicotine (NNN) is formed by synthetic or biological N-nitrosation of the tobacco alkaloid nornicotine. Following metabolic activation of NNN, DNA and protein adducts are formed releasing 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB), an actual biomarker to differentiate between tobacco smokers and passive smokers. NNN
Norbert H Kleinsasser et al.
Toxicology, 192(2-3), 171-177 (2003-10-29)
Myosmine, 3-(1-pyrroline-2-yl)pyridine, is an alkaloid found in tobacco plants. Recently, it was also detected in various edibles and staple foods. Whereas other tobacco alkaloids such as nicotine and nornicotine and their nitrosation products, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN), have been
Rumyana Simeonova et al.
Arhiv za higijenu rada i toksikologiju, 63(1), 7-14 (2012-03-28)
Myosmine [3-(1-pyrrolin-2-yl) pyridine] is an alkaloid structurally similar to nicotine, which is known to induce oxidative stress. In this study we investigated the effects of myosmine on enzymatic and non-enzymatic antioxidative defence in rat liver. Wistar rats received a single
Wolfgang Zwickenpflug et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(11), 1648-1656 (2005-08-05)
The alkaloid myosmine is present not only in tobacco products but also in various foods. Myosmine is easily nitrosated, yielding 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and the esophageal tobacco carcinogen N'-nitrosonornicotine. Due to its widespread occurrence, investigations on the metabolism and activation of
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