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Merck
CN

M8765

麦斯明

≥98%

别名:

3-(1-吡咯啉-2-基)吡啶

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关于此项目

经验公式(希尔记法):
C9H10N2
化学文摘社编号:
分子量:
146.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥98%
Form:
solid
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Quality Level

assay

≥98%

form

solid

storage temp.

2-8°C

SMILES string

C1CN=C(C1)c2cccnc2

InChI

1S/C9H10N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7H,2,4,6H2

InChI key

DPNGWXJMIILTBS-UHFFFAOYSA-N

Gene Information

rat ... Chrna4(25590)

Application

麦斯明可用作反应剂,通过N-亚硝化作用合成烟碱类衍生物。
烟碱

用于以下反应的反应物:
亚硝化反应
与过氧化氢的过氧化反应


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wolfgang Zwickenpflug et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(11), 1648-1656 (2005-08-05)
The alkaloid myosmine is present not only in tobacco products but also in various foods. Myosmine is easily nitrosated, yielding 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB) and the esophageal tobacco carcinogen N'-nitrosonornicotine. Due to its widespread occurrence, investigations on the metabolism and activation of
Krzysztof Noworyta et al.
Analytical chemistry, 84(5), 2154-2163 (2012-03-08)
Two electropolymerizable zinc porphyrins with receptor sites tailor-designed for selective recognition of the nicotine, cotinine, or myosmine alkaloids were synthesized. These were 5-(2-phenoxyacetamide)-10,15,20-tris(triphenylamino)porphyrinato zinc(II) 1 and 5-(2,5-phenylene-bis(oxy)diacetamide)-10,15,20-tris(triphenylamino)porphyrinato zinc(II) 2 featuring one and two pendant amide side "pincers", respectively, and three
W Zwickenpflug
Journal of agricultural and food chemistry, 48(2), 392-394 (2000-02-26)
N-Nitrosonornicotine (NNN) is formed by synthetic or biological N-nitrosation of the tobacco alkaloid nornicotine. Following metabolic activation of NNN, DNA and protein adducts are formed releasing 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB), an actual biomarker to differentiate between tobacco smokers and passive smokers. NNN



全球贸易项目编号

货号GTIN
M8765-500MG04061832544038
M8765-100MG04061832544021