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Merck
CN

M5814

Sigma-Aldrich

MKK6/SKK3, active human

≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution

别名:

MAP Kinase Kinase 6, MAP Kinase Kinase 6/SKK 3

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About This Item

MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.32

重组

expressed in E. coli

质量水平

检测方案

≥80% (SDS-PAGE)

形式

buffered aqueous solution

分子量

81 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... MAP2K6(5608)

特异性

Active in the phosphorylation of p38/SAPK2a

应用

Active enzyme for study of stress-activated protein kinases.
May be used for activation of p38α followed by phosphorylation of MBP.

单位定义

1 unit will activate 1 unit of p38/SAPK2 per minute. 1 unit of active p38/SAPK2 will incorporate 1 nanomole of phosphorus into myelin basic protein per minute.

外形

Solution in approx. 1 mg/ml in 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 0.1% 2-mercaptoethanol, 0.15 M NaCl, 0.03% Brij® L23, 270 mM sucrose, 0.2 mM PMSF, 1 mM benzamidine.

法律信息

Brij is a registered trademark of Croda International PLC

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)

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