质量水平
检测方案
≥95% (HPLC)
mp
192 °C (dec.) (lit.)
溶解性
DMSO: ≥20 mg/mL, clear, colorless to faintly yellow
储存温度
−20°C
SMILES字符串
Cl[H].COC(=O)C(C)(N)Cc1ccc(O)cc1
InChI
1S/C11H15NO3.ClH/c1-11(12,10(14)15-2)7-8-3-5-9(13)6-4-8;/h3-6,13H,7,12H2,1-2H3;1H
InChI key
OOVDEPZODSXAMU-UHFFFAOYSA-N
基因信息
human ... TH(7054)
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应用
α-甲基-DL-酪氨酸甲酯盐酸盐已被用于评估去甲肾上腺素的转换。
生化/生理作用
α-甲基-DL-酪氨酸(α-MT)可防止过度活性、嗅舔啃综合征、厌食症并改善苯丙胺的某些作用。它可抑制多巴胺的产生并防止突变体α-突触核蛋白刺激的细胞凋亡。
酪氨酸羟化酶抑制剂。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Antiamphetamine effects following inhibition of tyrosine hydroxylase
Journal of Pharmacology and Experimental Therapeutics, 151(3), 339-352 (1966)
Central sympathetic innervations to visceral and subcutaneous white adipose tissue
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 306(6), R375-R386 (2014)
The American journal of physiology, 277(4 Pt 1), E668-E677 (1999-10-12)
To further investigate neural effects on leptin and uncoupling proteins (UCPs), we studied in vivo perturbations intended to block adrenergic input to peripheral tissues. We examined plasma leptin, leptin mRNA, and adipose and muscle UCP subtype mRNA in rats treated
The American journal of physiology, 271(4 Pt 2), H1547-H1554 (1996-10-01)
To assess the effects of long-term pressure overload on sympathetic presynaptic components in the left ventricle, young adult male rats were subjected to surgical constriction of the suprarenal abdominal aorta. At 4 and 8 wk postsurgery, but not at 1
Brain research, 580(1-2), 164-170 (1992-05-15)
Dopamine (DA) in the medial preoptic area (MPOA) has been shown to facilitate male rat sexual behavior. However, injections of the catecholamine (CA) neurotoxin 6-OHDA into the MPOA did not impair copulation in tests 3 days after injection. In the
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