登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
4-(HO)C6H4CH2C(CH3)(NH2)CO2CH3 · HCl
化学文摘社编号:
分子量:
245.70
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
EC Number:
230-900-0
Beilstein/REAXYS Number:
5163031
MDL number:
InChI key
OOVDEPZODSXAMU-UHFFFAOYSA-N
InChI
1S/C11H15NO3.ClH/c1-11(12,10(14)15-2)7-8-3-5-9(13)6-4-8;/h3-6,13H,7,12H2,1-2H3;1H
SMILES string
Cl[H].COC(=O)C(C)(N)Cc1ccc(O)cc1
assay
≥95% (HPLC)
mp
192 °C (dec.) (lit.)
solubility
DMSO: ≥20 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
Quality Level
Gene Information
human ... TH(7054)
相关类别
Application
α-甲基-DL-酪氨酸甲酯盐酸盐已被用于评估去甲肾上腺素的转换。
Biochem/physiol Actions
α-甲基-DL-酪氨酸(α-MT)可防止过度活性、嗅舔啃综合征、厌食症并改善苯丙胺的某些作用。它可抑制多巴胺的产生并防止突变体α-突触核蛋白刺激的细胞凋亡。
酪氨酸羟化酶抑制剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease
Xu J, et al.
Nature Medicine, 8(6), 600-600 (2002)
Sonja C Schriever et al.
The Journal of clinical investigation, 130(11), 6093-6108 (2020-08-12)
Recent genome-wide association studies (GWAS) identified DUSP8, encoding a dual-specificity phosphatase targeting mitogen-activated protein kinases, as a type 2 diabetes (T2D) risk gene. Here, we reveal that Dusp8 is a gatekeeper in the hypothalamic control of glucose homeostasis in mice
G H Paalzow
The Journal of pharmacology and experimental therapeutics, 263(2), 470-479 (1992-11-01)
The present study shows that during the time course of the action of single doses, L-dopa induces multiphasic opposing effects on pain, recorded as vocalization during the presentation of electrical stimulation applied to the tail of normal rats. This indicates
J Venugopal et al.
Neurochemical research, 30(3), 315-323 (2005-07-16)
Wistar rats treated with alpha-methyl-DL-p-tyrosine methylester showed significant level of inhibition in the activity of Na+, K+ -ATPase, Mg2+ -ATPase and Ca2+ -ATPase enzymes in different regions of the brain. The enzyme activity was assayed in cerebral hemispheres, hypothalamus, thalamus
C K Murthy et al.
General and comparative endocrinology, 96(3), 427-437 (1994-12-01)
In our previous in vitro studies, [Ac-delta 3-Pro1, 4FD-Phe2, D-Trp3,6]-mGnRH (analog E) suppressed both gonadotropin-II (GTH-II) and growth hormone (GH) release stimulated by sGnRH and cGnRH-II. In the present study analog E significantly inhibited the increases in plasma GTH-II levels
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持