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M3184

Sigma-Aldrich

MG 624

≥98%

别名:

N,N,N-Triethyl-2-(4-trans-stilbenoxy)ethylammonium iodide

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About This Item

经验公式（希尔记法）:
C22H30INO
CAS号:
77257-42-2
分子量:
451.38
MDL编号:
MFCD00865233
UNSPSC代码:
12352200
PubChem化学物质编号:
24278547
NACRES:
NA.77

质量水平

100

方案

≥98%

溶解性

DMSO: ≤22 mg/mL
H2O: insoluble

储存温度

2-8°C

SMILES字符串

[I-].CC[N+](CC)(CC)CCOc1ccc(cc1)\C=C\c2ccccc2

InChI

1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;

InChI key

RDTKUZXIHMTSJO-UEIGIMKUSA-M

基因信息

human ... CHRNA7(1139)

生化/生理作用

Nicotinic acetylcholine receptor antagonist; selectively inhibits neuronal nicotinic α-bungarotoxin sensitive receptors that contain the α7 subunit.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
050K4620

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C Gotti et al.
British journal of pharmacology, 124(6), 1197-1206 (1998-08-28)
1. Starting from the structure of an old 4-oxystilbene derivate with ganglioplegic activity (MG624), we synthesized two further derivates (F2 and F3) and two stereoisomers of F3 (F3A and F3B), and studied their selective effect on neuronal nicotinic acetylcholine receptor
Glenn W Vicary et al.
Respiratory research, 18(1), 115-115 (2017-06-04)
Tobacco-related chronic lung diseases are characterized by alterations in lung architecture leading to decreased lung function. Knowledge of the exact mechanisms involved in tobacco-induced tissue remodeling and inflammation remains incomplete. We hypothesize that nicotine stimulates the expression of extracellular matrix

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