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Merck
CN

M2892

Sigma-Aldrich

Methylphenidate hydrochloride

别名:

threo-Methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride, Ritalin hydrochloride

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About This Item

经验公式(希尔记法):
C14H19NO2 · HCl
CAS号:
分子量:
269.77
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.77

质量水平

药品控制

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

应用

forensics and toxicology

创始人

Johnson & Johnson

SMILES字符串

Cl[H].COC(=O)C(C1CCCCN1)c2ccccc2

InChI

1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H

InChI key

JUMYIBMBTDDLNG-UHFFFAOYSA-N

基因信息

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相关类别

生化/生理作用

CNS stimulant; releases catecholamines; potent inhibitor of dopamine reuptake

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R Kuczenski et al.
The Journal of pharmacology and experimental therapeutics, 296(3), 876-883 (2001-02-22)
The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit hyperactivity disorder has risen dramatically in recent years. The relative roles of dopamine, norepinephrine, and serotonin in the therapeutic action of these drugs was assessed by comparing the
Robert Lew et al.
Psychopharmacology, 237(11), 3435-3446 (2020-08-20)
Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains unclear whether intravenous (i.v.) administration would
Clinical practice. Attention deficit-hyperactivity disorder in children and adolescents.
Heidi M Feldman et al.
The New England journal of medicine, 370(9), 838-846 (2014-02-28)
Pleun J de Raaf et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(25), 3056-3060 (2013-07-31)
A 64-year-old woman with metastatic rectal cancer is admitted to the acute palliative care unit of our cancer center because of debilitating fatigue. She had been diagnosed with metastatic disease in 2009, when liver metastases were found 1 year after
Natalie Grizenko et al.
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 58(11), 632-639 (2013-11-20)
Examine the short-term (acute) effects of methylphenidate (MPH) on math performance in children with attention-deficit hyperactivity disorder (ADHD) and what factors predict improvement in math performance. One hundred ninety-eight children with ADHD participated in a double-blind, placebo-controlled, randomized crossover MPH

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