M2892

Methylphenidate hydrochloride

Name: Methylphenidate hydrochloride
Brand: SIGMA

CNS stimulant

别名:

threo-Methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride, Ritalin hydrochloride

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经验公式（希尔记法）:

C₁₄H₁₉NO₂ · HCl

化学文摘社编号:

298-59-9

分子量:

269.77

NACRES:

NA.77

PubChem Substance ID:

24896775

UNSPSC Code:

41116107

EC Number:

206-065-3

MDL number:

MFCD00058191

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产品名称

Methylphenidate hydrochloride,

InChI key

JUMYIBMBTDDLNG-UHFFFAOYSA-N

InChI

1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H

SMILES string

Cl[H].COC(=O)C(C1CCCCN1)c2ccccc2

description

Drug Control: Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
kontrollierte Droge in Deutschland

Quality Level

200

Gene Information

human ... SLC6A2(6530), SLC6A3(6531)

application(s)

forensics and toxicology

originator

Johnson & Johnson

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Biochem/physiol Actions

CNS stimulant; releases catecholamines; potent inhibitor of dopamine reuptake

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

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Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine.

R Kuczenski et al.

The Journal of pharmacology and experimental therapeutics, 296(3), 876-883 (2001-02-22)

The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit hyperactivity disorder has risen dramatically in recent years. The relative roles of dopamine, norepinephrine, and serotonin in the therapeutic action of these drugs was assessed by comparing the

The rate of dasotraline brain entry is slow following intravenous administration.

Robert Lew et al.

Psychopharmacology, 237(11), 3435-3446 (2020-08-20)

Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains unclear whether intravenous (i.v.) administration would

Methylphenidate and/or a nursing telephone intervention for fatigue in patients with advanced cancer: a randomized, placebo-controlled, phase II trial.

Eduardo Bruera et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(19), 2421-2427 (2013-05-22)

Cancer-related-fatigue (CRF) is common in advanced cancer. The primary objective of the study was to compare the effects of methylphenidate (MP) with those of placebo (PL) on CRF as measured using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) fatigue

Clinical practice. Attention deficit-hyperactivity disorder in children and adolescents.

Heidi M Feldman et al.

The New England journal of medicine, 370(9), 838-846 (2014-02-28)

Can you help me feel less exhausted all the time?

Pleun J de Raaf et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(25), 3056-3060 (2013-07-31)

A 64-year-old woman with metastatic rectal cancer is admitted to the acute palliative care unit of our cancer center because of debilitating fatigue. She had been diagnosed with metastatic disease in 2009, when liver metastases were found 1 year after

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Methylphenidate hydrochloride

CNS stimulant

选择尺寸

关于此项目

主要文件

属性

产品名称

InChI key

InChI

SMILES string

description

drug control

Quality Level

Gene Information

application(s)

originator

相关类别

说明

Biochem/physiol Actions

Features and Benefits

Legal Information

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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