所有图片(1)
About This Item
经验公式（希尔记法）:
C7H15NO4
CAS号:
分子量:
177.20
Beilstein:
1524564
MDL编号:
UNSPSC代码:
51102829
PubChem化学物质编号:
NACRES:
NA.32
推荐产品
生物来源
synthetic (organic)
质量水平
方案
≥98%
表单
powder
溶解性
methanol: 10 mg/mL, clear, colorless
抗生素抗菌谱
viruses
作用机制
enzyme | inhibits
储存温度
−20°C
SMILES字符串
CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI
1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1
InChI key
AAKDPDFZMNYDLR-XZBKPIIZSA-N
基因信息
mouse ... Gaa(14387) , Glb1(12091) , Treh(58866)
rat ... Man2a1(25478) , Si(497756)
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一般描述
Chemical structure: glucosamine
生化/生理作用
Interferes with metabolism of N-linked glycoproteins by inhibition of glucosidase.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Diego A Caraballo et al.
G3 (Bethesda, Md.), 10(2), 755-768 (2019-12-05)
UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and Caenorhabditis genomes harbor two uggt gene copies that exhibit differences
P F Daniel et al.
American journal of medical genetics, 42(4), 586-592 (1992-02-15)
In agreement with reports from other laboratories, we have shown that patients with the juvenile or late infantile forms of neuronal ceroid-lipofuscinosis (NCL) have greatly increased levels (5-fold to 20-fold) of dolichyl pyrophosphoryl oligosaccharides in their cerebral gray matter. Oligosaccharides
J C Ridruejo et al.
Biochimica et biophysica acta, 993(2-3), 179-185 (1989-12-08)
Castanospermine, 1-deoxynojirimycin, and N-methyl-1-deoxynojirimycin, three well-characterized inhibitors of the glucosidases involved in the processing of N-linked oligosaccharides, did not affect the biosynthesis or the secretion of exoglucanases (EC 3.2.1.58) from Saccharomyces cerevisiae and Candida albicans but inhibited the activity itself.
G C Trudel et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 68(12), 1411-1418 (1990-12-01)
Treatment of chick myoblasts with the glucosidase inhibitors bromoconduritol (BCD) or N-methyl-1-deoxynojirimycin (MDJN), but not the mannosidase I inhibitor 1-deoxymannojirimycin (ManDJN), decreased their rate of adhesion to fibronectin and laminin and increased their rate of adhesion to collagen types I
G C Trudel et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 66(10), 1119-1125 (1988-10-01)
It has recently been reported that the glucosidase I inhibitor, N-methyl-1-deoxynojirimycin (MDJN), inhibits myoblast fusion whereas the mannosidase inhibitor, 1-deoxymannojirimycin (ManDJN), has no effect on fusion. We now report that bromoconduritol, which is an active-site-directed covalent inhibitor of glucosidase II
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