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Merck
CN

M1523

Sigma-Aldrich

蝇蕈醇

powder

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别名:
3-羟基-5-氨甲基-异噁唑, 5-氨甲基-3-异噁唑醇, 5-氨甲基-3-羟基-异噁唑, Pantherine, 毒蝇蕈醇
经验公式(希尔记法):
C4H6N2O2
CAS号:
分子量:
114.10
Beilstein:
1618960
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

形式

powder

质量水平

颜色

white to off-white

储存温度

2-8°C

SMILES字符串

NCC1=CC(=O)NO1

InChI

1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)

InChI key

ZJQHPWUVQPJPQT-UHFFFAOYSA-N

基因信息

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一般描述

蝇蕈醇(Muscimol)是一种异噁唑类精神性物质,主要存在于毒蝇伞(Amanita muscaria)等菇类中。可降低大脑糖代谢,提高脑中的5-羟色胺浓度。蝇蕈醇具有致幻作用。与感知曲解、恶心和呕吐有关联。

应用

蝇蕈醇已用于:
  • 降低外侧杏仁核(LA)中条件性恐惧表达
  • 消除雪貂的皮层细胞反应
  • 灭活斑胸草雀中的巢皮层外侧巨细胞核(LMAN)

生化/生理作用

GABAA受体激动剂。

特点和优势

受体分类和信号转导手册的GABAA受体GABAC受体页面重点介绍了该化合物。想要浏览手册的其他页面, 请单击此处
该化合物是神经科学研究推荐产品。点击此处 ,查看更多神经科学精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问 sigma.com/discover-bsm

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

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