所有图片(1)
About This Item
经验公式（希尔记法）:
C11H14N2O · C4H4O4
CAS号:
分子量:
306.31
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to beige
溶解性
H2O: >3 mg/mL, clear (warmed)
储存温度
−20°C
SMILES字符串
[H]\C(=C(/[H])C(O)=O)C(O)=O.CC(N)Cc1c[nH]c2ccc(O)cc12
InChI
1S/C11H14N2O.C4H4O4/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11;5-3(6)1-2-4(7)8/h2-3,5-7,13-14H,4,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
YQNHFSXRABPJLP-BTJKTKAUSA-N
基因信息
human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)
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生化/生理作用
5-HT 2 血清素受体激动剂。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
P D Feldman
Journal of the autonomic nervous system, 56(1-2), 119-124 (1995-12-05)
Spontaneous neuronal activity in the solitary tract nucleus was recorded extracellularly in a brain slice preparation during bath-application of 5-HT1 and 5-HT2 receptor-selective agonists and antagonists. The 5-HT1A/5-HT1B agonist 5-carboxamidotryptamine depressed activity in 20 of 25 neurons studied. The remaining
A M Ismaiel et al.
Journal of medicinal chemistry, 33(2), 755-758 (1990-02-01)
alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were synthesized and examined at serotonin (5-HT) binding sites because there is relatively little documentation as to their selectivity and because they
Ralf Buettner et al.
Molecular therapy oncolytics, 14, 149-158 (2019-06-19)
The immunosuppressive agent leflunomide has been used in the treatment of over 300,000 patients with rheumatoid arthritis. Its active metabolite, teriflunomide (Ter), directly inhibits dihydroorotate dehydrogenase (DHODH), an enzyme involved in nucleoside synthesis. We report that Ter not only shows
G P Leung et al.
The Journal of physiology, 519 Pt 3, 657-667 (1999-08-24)
1. The short-circuit current (Isc) technique was used to study the role of 5-hydroxytryptamine (5-HT) in the regulation of anion secretion in cultured rat cauda epididymal epithelia. 2. 5-HT, the 5-HT1B-selective agonist 5-nonyloxytryptamine (5-NOT) and the 5-HT2B-selective agonist alpha-methyl-5-hydroxytryptamine (alpha-methyl-5-HT)
Dmitrii Zabelskii et al.
Nature communications, 11(1), 5707-5707 (2020-11-13)
Phytoplankton is the base of the marine food chain as well as oxygen and carbon cycles and thus plays a global role in climate and ecology. Nucleocytoplasmic Large DNA Viruses that infect phytoplankton organisms and regulate the phytoplankton dynamics encompass
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