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线性分子式:
LiCl
化学文摘社编号:
分子量:
42.39
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-212-3
MDL number:
Assay:
≥99%
Grade:
Molecular Biology
Form:
powder
Solubility:
H2O: 100 mg/mL at 20 °C, clear, colorless
产品名称
氯化锂, Molecular Biology, ≥99%
InChI key
KWGKDLIKAYFUFQ-UHFFFAOYSA-M
InChI
1S/ClH.Li/h1H;/q;+1/p-1
SMILES string
[Li+].[Cl-]
grade
Molecular Biology
assay
≥99%
form
powder
mp
605 °C (lit.)
solubility
H2O: 100 mg/mL at 20 °C, clear, colorless
anion traces
sulfate (SO42-): ≤0.01%
cation traces
Ba: ≤0.003%
Fe: ≤0.001%
K: ≤0.01%
Na: ≤0.20%
heavy metals (as Pb): ≤0.002%
foreign activity
DNase, NICKase, RNase, protease, none detected
Quality Level
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Application
可用于选择性沉淀RNA。
氯化锂已用于:
- 制备染色质免疫沉淀用洗涤缓冲液
- 3-(4,5-二甲基-2-噻唑基)-2,5-二苯基溴化四唑(MTT)检测
- 处理老化成肌细胞,分析其作为糖原合成酶激酶(GSK)抑制剂对于wingless/tailess(wnt)信号传导通路的影响
Biochem/physiol Actions
氯化锂可用于抑制糖原合成酶激酶(GSK)。在无毒性的较低浓度下,它还具有抗炎作用。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells
Lacazette E
Biochemistry and Molecular Biology Education, 45(2), 152-160 (2017)
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts
Vertino AM, et al.
Molecular Biology of the Cell, 16(4), 2039-2048 (2005)
mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms
Liu R, et al.
Molecular and cellular biology, 28(23), 7236-7244 (2008)
Alessandro Di Maio et al.
EvoDevo, 6, 17-17 (2015-07-15)
Wnt signaling is one of the earliest and most highly conserved regulatory pathways for the establishment of the body axes during regeneration and early development. In regeneration, body axes determination occurs independently of tissue rearrangement and early developmental cues. Modulation
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