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Merck
CN

L7386

溶葡球菌酶 来源于溶葡萄球菌

≥500 units/mg protein, lyophilized powder

别名:

甘氨酰-甘氨酸内肽酶

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关于此项目

化学文摘社编号:
9011-93-2
UNSPSC Code:
12352204
NACRES:
NA.54
EC 号:
3.4.24.75 (BRENDA, IUBMB)
MDL number:
MFCD00131556

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产品名称

溶葡球菌酶 来源于溶葡萄球菌, lyophilized powder, Protein 50-70 % by biuret, ≥500 units/mg protein

biological source

microbial (Staphylococcus staphylotyticus)

form

lyophilized powder

specific activity

≥500 units/mg protein

mol wt

25 kDa

composition

Protein, 50-70% biuret

packaging

pkg of (sold on basis of mg protein)

solubility

water: 2.00-2.10 mg/mL, clear to slightly hazy, colorless to light yellow

antibiotic activity spectrum

Gram-positive bacteria

application(s)

diagnostic assay manufacturing
diagnostic assay manufacturing

mode of action

cell wall synthesis | interferes

shipped in

wet ice

storage temp.

−20°C

Quality Level

300

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Other Notes

一个单位在25°C和pH 7.5条件下，在6.0 m反应混合物中可使 金黄色酿脓葡萄球菌 细胞悬浮液的浊度（A620）在10分钟内由0.250降至0.125。

Biochem/physiol Actions

溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键，它已被发现可用于细胞裂解，并具有潜在的抗菌治疗作用。
活性最佳pH：约 7.5

General description

化学结构：多肽

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H334

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000515709
0000515709
0000515710
0000515710
0000515708

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Ian R Monk et al.
Nature communications, 10(1), 3067-3067 (2019-07-13)
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, we investigate a suppressor mutant that arose
Judy J J Ou et al.
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts.
Catherine Bennett et al.
International forum of allergy & rhinology, 9(8), 918-925 (2019-06-05)
Chronic rhinosinusitis (CRS) is a common disease, often refractory to conventional antimicrobial treatment. In this study we investigate the antimicrobial and anti-inflammatory effects of adding kappa-carrageenan to a commercially available sinus rinse. Kappa-carrageenan was added to Flo CRS and Flo
Dafne Bongiorno et al.
MicrobiologyOpen, 9(5), e1017-e1017 (2020-04-03)
Methicillin-resistant S. aureus has been reported as the main pathogen involved in chronic infections, osteomyelitis, and prosthetic joint infections. The host/pathogen interaction is dynamic and requires several changes to promote bacterial survival. Here, we focused on the internalization and persistence
Igor Belyansky et al.
The Journal of surgical research, 171(2), 409-415 (2011-06-24)
Lysostaphin (LS), a naturally occurring Staphylococcal endopeptidase, has the ability to penetrate biofilm, and has been identified as a potential antimicrobial to prevent mesh infection. The goals of this study were to determine if LS adhered to porcine mesh (PM)
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实验方案

GenElute™ Bacterial Genomic DNA Kit Protocol (NA2100, NA2110, NA2120)

GenElute™ Bacterial Genomic DNA Kit protocol describes a simple and convenient way for the isolation of pure genomic DNA from bacteria.

GenElute™细菌基因组DNA试剂盒实验方案（NA2100、NA2110、NA2120）

的GenElute™细菌基因组DNA试剂盒提供了一种从细菌中分离纯基因组DNA的简便方法。

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