L6292
赖诺普利
≥98% (HPLC), Angiotensin converting enzyme (ACE) inhibitor., solid
别名:
MK-521, （S）-1- [N2-（1-羧基-3-苯丙基）-赖氨酰脯氨酸 二水合物
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C21H31O5N3 · 2H2O
化学文摘社编号:
分子量:
441.52
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
赖诺普利, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
solid
color
white
solubility
H2O: ≥10 mg/mL, DMSO: ~6.5 mg/mL (with heating and sonicating)
storage temp.
2-8°C
SMILES string
[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI
1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI key
CZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Information
human ... ACE(1636)
Application
赖诺普利已被用于研究杜氏营养不良症小鼠的抗纤维化作用。它已被用于研究经过长期达贝泊汀处理后的 TGR（mRen2）27 （携带小鼠 Ren-2 基因的转基因大鼠）大鼠的肾结构和功能的变化。
Biochem/physiol Actions
血管紧张素转换酶（ACE）抑制剂。
Features and Benefits
该化合物是位于美国新泽西Kenilworth的Merck & Co., Inc.开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单， 请单击此处。
Still not finding the right product?
Explore all of our products under 赖诺普利
signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
target_organs
Kidney
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jason V Baker et al.
PloS one, 7(10), e46894-e46894 (2012-10-20)
Treatments that reduce inflammation and cardiovascular disease (CVD) risk among individuals with HIV infection receiving effective antiretroviral therapy (ART) are needed. We conducted a 2 × 2 factorial feasibility study of lisinopril (L) (10 mg daily) vs L-placebo in combination
Anne-Roos S Frenay et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 13(2), 232-238 (2012-01-28)
Erytropoietin (EPO) has cytoprotective and angiogenic properties and has a beneficial effect in ischaemic conditions. Since the development of renal interstitial abnormalities are often associated with ischaemia, we studied the effects of the long-acting EPO analogue darbepoetin alpha (DA) on
Saleh Yazdani et al.
PloS one, 7(11), e50209-e50209 (2012-11-29)
Proteinuria is an important cause of progressive tubulo-interstitial damage. Whether proteinuria could trigger a renal lymphangiogenic response has not been established. Moreover, the temporal relationship between development of fibrosis, inflammation and lymphangiogenesis in chronic progressive kidney disease is not clear
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L6292-100MG | 04061833958711 |
| L6292-250MG | 04061833026496 |