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Merck
CN

L4402

Sigma-Aldrich

溶葡球菌酶 来源于溶葡萄球菌

BioUltra, ≥97% (SDS-PAGE), Protein 40-60 % by biuret, ≥2,000 units/mg protein

别名:

甘氨酰-甘氨酸内肽酶

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54

生物来源

bacterial (Staphylococcus sp.)

质量水平

产品线

BioUltra

方案

≥97% (SDS-PAGE)

表单

lyophilized powder

比活

≥2,000 units/mg protein

分子量

25 kDa

组成

Protein, 40-60% biuret

浓度

40—60% protein

技术

cell based assay: suitable

适用性

suitable for cell lysis

抗生素抗菌谱

Gram-positive bacteria

应用

diagnostic assay manufacturing

作用机制

cell wall synthesis | interferes

储存温度

−20°C

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一般描述

包装尺寸基于蛋白质含量
化学结构:肽

生化/生理作用

溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键,它已被发现可用于细胞裂解,并具有潜在的抗菌治疗作用。
活性最佳pH:约 7.5

单位定义

一个单位在 25°C 和 pH 7.5 条件下,在 6.0 ml 反应混合物中可使金黄色酿脓葡萄球菌细胞悬浮液的浊度(A620)在 10 分钟内由 0.250 降至 0.125。

外形

含有磷酸钾缓冲盐和氯化钠

制备说明

亲和纯化

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象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Johnny Gutierrez et al.
Open forum infectious diseases, 6(4), ofz090-ofz090 (2019-04-27)
Staphylococcus aureus (SA) bacteremia often requires a long treatment duration with antibiotics to prevent relapse due to the ability of SA to establish reservoirs of infection in sites such as heart and bone. These metastatic sites of infection cannot be
Yuliya Yurko et al.
Surgical innovation, 19(1), 20-26 (2011-07-12)
Naturally occurring antimicrobial peptides are possibly the "next frontier" in infection prevention. Binding them to mesh could reduce the rate of mesh infections. This study identifies an antimicrobial agent capable of significant antibacterial activity when bound to mesh. Lysozyme, human
Shaw R Gargis et al.
Applied and environmental microbiology, 76(20), 6944-6946 (2010-08-24)
Resistance to lysostaphin, a staphylolytic glycylglycine endopeptidase, is due to a FemABX-like immunity protein that inserts serines in place of some glycines in peptidoglycan cross bridges. These modifications inhibit both binding of the recombinant cell wall targeting domain and catalysis
Thomas S Lawson et al.
Journal of clinical laboratory analysis, 25(5), 359-365 (2011-09-16)
Aspects of the fluorescence in situ hybridization (FISH) method for the detection of clinically important bacteria, such as Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli, were investigated for optimization. Various approaches to optimizing the FISH procedure were taken and different
R Satishkumar et al.
Nanotechnology, 22(50), 505103-505103 (2011-11-24)
The objective of this paper was to study the effect of antibody-directed targeting of S. aureus by comparing the activities of lysostaphin conjugated to biodegradable polylactide nanoparticles (NPs) in the presence and in the absence of co-immobilized anti-S. aureus antibody.

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