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L4391

Sigma-Aldrich

脂多糖 来源于大肠杆菌 0111:B4

γ-irradiated, BioXtra, suitable for cell culture

别名:

LPS

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4 L
CN¥2,166.96

CN¥2,166.96

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4 L
CN¥2,166.96

About This Item

CAS号:
93572-42-0
EC 号:
297-473-0
MDL编号:
MFCD00164401
UNSPSC代码:
12352211
NACRES:
NA.75

CN¥2,166.96

请联系客服了解存货情况
获取大包装报价

生物来源

Escherichia coli (O111:B4)

质量水平

300

无菌性

γ-irradiated

产品线

BioXtra

表单

lyophilized powder

纯化方式

gel-filtration chromatography

储存条件

desiccated

技术

cell based assay: suitable
cell culture | mammalian: suitable

杂质

<1% Protein (Lowry)

溶解性

H2O: 5 mg/mL, slightly hazy

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此商品
114529P3532PX0530
Phenol red (phenolsulfonphthalein) Reag. Ph Eur

159375

Phenol red

Phenol Red ACS reagent

114529

Phenol Red

Phenol Red powder, BioReagent, suitable for cell culture

P3532

Phenol Red

Phenol Red Meets ACS Specifications GR ACS

PX0530

Phenol Red

form

solid

form

powder

form

powder

form

powder

storage temp.

no temp limit

storage temp.

room temp

storage temp.

room temp

storage temp.

10-30°C

assay

98.0-102.0% (bromatometric, calculated on dried substance)

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

mp

>300 °C

mp

-

mp

>300 °C

mp

>300 °C

agency

reag. Ph. Eur.

agency

-

agency

-

agency

-

一般描述

脂多糖 (LPS) 是由脂质和多糖组成的复杂分子，主要存在于革兰氏阴性菌的外膜中。LPS 由脂质 A、核心低聚糖 (core) 和 O 特异性多糖或 O 抗原 (Oag) 组成，固定在细菌外膜上，脂质 A 主要负责其相关毒性。作为促炎反应的有效激活剂，LPS 参与多种哺乳动物细胞，包括巨噬细胞、单核细胞和内皮细胞。在保护革兰氏阴性菌免受环境胁迫的同时，LPS 也在感染过程中触发先天免疫系统的识别。

应用

脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式（PAMP）的Toll样受体蛋白家族成员Toll样受体4（TLR4）刺激先天性免疫系统细胞。
该LPS血清型已用于刺激B细胞并在人肝细胞中诱导NOS。

生化/生理作用

脂多糖是绝大多数革兰氏阴性菌细胞壁的一种主要组成成分。它是一种高免疫原性抗原，具有增强针对可溶性抗原免疫应答的能力。LPS还可作为来自小鼠、兔、鸡、牛、仓鼠和人骨髓来源的B淋巴细胞的一种特异性促分裂原。

特点和优势

  • 高纯度化合物适用于各种研究应用

重悬

脂多糖以经γ-射线处理的冻干粉形式提供。如需重悬，可将1 ml无菌的平衡盐溶液或组织培养基加入至小瓶（1 mg）中并轻轻晃动直至粉末溶解。重悬后的产品可采用无菌的平衡盐溶液或组织培养基进一步被稀释至所需的工作浓度。

其他说明

为了全面了解我们针对客户研究提供的各种脂多糖产品，建议您访问我们的碳水化合物分类页面。
如需了解生化试剂系列的更多信息，请填写此表。

相关产品

产品编号
说明
价格

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H300

危险分类

Acute Tox. 2 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    0000297998
    0000252542
    0000252542
    0000187965

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