所有图片(4)

主要文件

L3012

脂多糖来源于大肠杆菌 0111:B4

Name: 脂多糖 来源于<I>大肠杆菌 </I> 0111:B4
Brand: SIGMA
Price: 1459.47 CNY
Availability: InStock

purified by gel-filtration chromatography

别名:

LPS

登录查看公司和协议定价

选择尺寸

0.5 MG

¥1,459.47

目录价¥4,864.92节省 70%

国内现货，预计发货时间2025年4月16日详情

获取大包装报价

所有图片(4)

选择尺寸

变更视图

0.5 MG

¥1,459.47

About This Item

CAS号:

93572-42-0

EC 号:

297-473-0

MDL编号:

MFCD00164401

UNSPSC代码:

12352201

NACRES:

NA.25

¥1,459.47

目录价¥4,864.92节省 70%

国内现货，预计发货时间2025年4月16日详情

获取大包装报价

该产品是从E. coli血清型 O111:B4中提取，胶过滤纯化。来源菌株由私人提供。该LPS血清型已用于刺激B细胞并诱导人肝细胞的NOS。

应用

脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式（PAMP）的Toll样受体蛋白家族成员Toll样受体4（TLR4）刺激先天性免疫系统细胞。

生化/生理作用

脂多糖（LPS）位于膜的外层，并且暴露在无包膜菌株的细胞表面。它们有助于维持外层膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的破坏。

制备说明

本品溶于水(5 mg/ml)或细胞培养基（1 mg/ml），得到浑浊的淡黄色溶液。以中更为浓缩但仍然模糊的溶液（20 mg/ml）可形成于涡旋并升温至70-80^oC后。脂多糖是在每种溶剂中都形成胶束的分子。在水和磷酸盐缓冲液中都能观察到模糊的溶液。有机溶剂也不会产生更为清澈的溶液。甲醇可产生具有漂浮物的混浊悬浮液，而水则能产生均匀模糊的溶液。

其他说明

为了全面了解我们针对客户研究提供的各种脂多糖产品，建议您访问我们的碳水化合物分类页面。

警示用语：

Danger

危险声明

H300

预防措施声明

P264 - P270 - P301 + P310 - P405 - P501

危险分类

Acute Tox. 2 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

技术规格说明书

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

RANKL-induced M1 macrophages are involved in bone formation.

Rong Huang et al.

Bone research, 5, 17019-17019 (2017-12-22)

The activation of M1 macrophages can be achieved by stimulating them with lipopolysaccharide (LPS) and interferon-γ (IFN-γ). However, M1 can be found under physiological conditions without any pathological stimuli. This study aimed to understand the involvement of RANKL-induced M1 macrophages

Immunization with Mycobacterium vaccae induces an anti-inflammatory milieu in the CNS: Attenuation of stress-induced microglial priming, alarmins and anxiety-like behavior.

Matthew G Frank et al.

Brain, behavior, and immunity, 73, 352-363 (2018-05-29)

Exposure to stressors induces anxiety- and depressive-like behaviors, which are mediated, in part, by neuroinflammatory processes. Recent findings demonstrate that treatment with the immunoregulatory and anti-inflammatory bacterium, Mycobacterium vaccae (M. vaccae), attenuates stress-induced exaggeration of peripheral inflammation and stress-induced anxiety-like

Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration.

Sheng Song et al.

Molecular neurobiology, 56(4), 2653-2669 (2018-07-28)

Environmental toxicant exposure has been strongly implicated in the pathogenesis of Parkinson's disease (PD). Clinical manifestations of non-motor and motor symptoms in PD stem from decades of progressive neurodegeneration selectively afflicting discrete neuronal populations along a caudo-rostral axis. However, recapitulating

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.

Norihiko Takeda et al.

Genes & development, 24(5), 491-501 (2010-03-03)

Hypoxic response and inflammation both involve the action of the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha. Previous studies have revealed that both HIF-alpha proteins are in a number of aspects similarly regulated post-translationally. However, the functional interrelationship of these two

Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus.

Susanne A Wolf et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(9), 3121-3128 (2009-05-13)

To understand the link between peripheral immune activation and neuronal precursor biology, we investigated the effect of T-cell activation on adult hippocampal neurogenesis in female C57Bl/6 mice. A peripheral adaptive immune response triggered by adjuvant-induced rheumatoid arthritis (2 microg/microl methylated

查看所有相关文献

商品

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

此商品	I4028	WH0003553M1	I7534
I3642 抗-白介素1单克隆抗体β 小鼠抗	I4028 Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse	WH0003553M1 Monoclonal Anti-IL1B antibody produced in mouse	I7534 Monoclonal Anti-Interleukin-1α antibody produced in mouse
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin
Gene Information human ... IL1B(3553)	Gene Information human ... IL18R1(8809)	Gene Information human ... IL1B(3553)	Gene Information human ... IL1A(3552)
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone 8516.311, monoclonal	clone 70625.111, monoclonal	clone 2A8, monoclonal	clone 4414, monoclonal
species reactivity human	species reactivity human	species reactivity human	species reactivity human

主要文件

脂多糖 来源于大肠杆菌 0111:B4

purified by gel-filtration chromatography

选择尺寸

选择尺寸

About This Item

推荐产品

属性

生物来源

质量水平

表单

纯化方式

杂质

颜色

溶解性

运输

储存温度

相关类别

比较类似商品

此商品

说明

一般描述

应用

生化/生理作用

制备说明

其他说明

相关产品

相关产品

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

储存分类代码

WGK

闪点(°F)

闪点(°C)

文件

分析证书(COA)

已有该产品？

同行评审论文

技术文章和实验方案

商品

相关内容

技术服务

脂多糖来源于大肠杆菌 0111:B4