推荐产品
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]22/D −35°, c = 0.38 in H2O(lit.)
颜色
white to beige
溶解性
H2O: 5 mg/mL, clear
创始人
Roche
SMILES字符串
O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@@]12CCCC[C@@]13CCN(CC=C)[C@@H]2Cc4ccc(O)cc34
InChI
1S/C19H25NO.C4H6O6/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19;5-1(3(7)8)2(6)4(9)10/h2,6-7,13,16,18,21H,1,3-5,8-12H2;1-2,5-6H,(H,7,8)(H,9,10)/t16-,18+,19+;1-,2-/m01/s1
InChI key
FWMLYVACGDQRFU-ZTMWJVNESA-N
基因信息
human ... OPRD1(4985) , OPRM1(4988)
生化/生理作用
Partial agonist (antagonist) at μ and δ opioid receptors.
特点和优势
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
注意
Photosensitive
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Ying-Chen Chen et al.
International journal of nanomedicine, 10, 7265-7274 (2015-12-15)
To alleviate the inherent problems of amphotericin B (AmB), such as poor water solubility and nephrotoxicity, a novel self-assembling mixed polymeric micelle delivery system based on lecithin and combined with amphiphilic polymers, Pluronic(®), Kolliphor(®), d-alpha tocopheryl polyethylene glycol succinate, and
Ling-Chun Chen et al.
International journal of nanomedicine, 11, 1557-1566 (2016-05-05)
Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility
Tzu-Pin Li et al.
Scientific reports, 7(1), 10674-10674 (2017-09-08)
This study involved physical and pharmacokinetic characterizations of trans-resveratrol (t-Rev)-loaded saLMPMs which attempted to improve t-Rev's pharmacokinetic profiles and bioavailability resolving hurdles limiting its potential health benefits. The optimal formulation consisted of t-Rev, lecithin, and Pluronic
Michael E Johnson et al.
Nanomaterials (Basel, Switzerland), 10(2) (2020-02-06)
A newly synthesized nanomaterial known as KxW7O22 (KxWO) exhibits a stable room-temperature ferroelectric property. This unique ferroelectric property has revealed that KxWO is a promising material for application in a breath sensor, which can be used for patients to monitor
Anushree Seth et al.
International journal of nanomedicine, 7, 5129-5136 (2012-10-12)
The influence of morphology and surface properties on the therapeutic efficacy of degradable polymeric microparticles has not been well understood. One of the primary reasons for this is the limited ability to fabricate microparticles with controlled morphology and surface properties.
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