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Merck
CN

L1011

拉贝洛尔 盐酸盐

>98% (TLC), Competitive β-adrenoceptor antagonist., powder

别名:

2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzamide hydrochloride

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关于此项目

经验公式(希尔记法):
C19H24N2O3 · HCl
化学文摘社编号:
分子量:
364.87
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
251-211-1
MDL number:
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产品名称

拉贝洛尔 盐酸盐, >98% (TLC), powder

InChI key

WQVZLXWQESQGIF-UHFFFAOYSA-N

InChI

1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H

SMILES string

Cl.CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(N)=O

assay

>98% (TLC)

form

powder

color

white

Quality Level

originator

Schering Plough

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Biochem/physiol Actions

Competitive β-adrenoceptor antagonist.

Features and Benefits

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E Riva et al.
British journal of pharmacology, 104(4), 823-828 (1991-12-01)
1. We compared the alpha 1-, alpha 2- and beta 1-adrenoceptor blocking potencies of labetalol with those of its two stereoisomers (RR and SR) in pithed rats and in homogenized rat cerebral cortex and heart. 2. In pithed rats, labetalol
R Jaboureck-Bouttier et al.
Hypertension in pregnancy, 18(3), 239-247 (1999-12-10)
Increased lipid peroxidation is a putative causal factor for preeclampsia. Because oxygen free radicals are involved in inducing the lipid oxidation chain reaction, we evaluated two beta adrenoreceptor blockers, labetalol and metoprolol, currently used for treating hypertension with regard to
S C Fagan et al.
Experimental neurology, 150(1), 153-158 (1998-03-26)
We examined the relationship between acute hypertension following cerebral embolization and subsequent hemorrhagic transformation (HT) in a rabbit embolic stroke model. We have shown previously that the likelihood and severity of hemorrhage were significantly correlated with the magnitude of an
Mohamed O Amin et al.
Mikrochimica acta, 186(8), 503-503 (2019-07-05)
The use of carbon black-Fe3O4 magnetic nanocomposite (CB-Fe3O4) as a probe for surface-enhanced laser desorption ionization mass spectrometry (SELDI-MS) with a high extraction efficiency and sensitive detection is described. The magnetic nanocomposite was synthesized and fully characterized using X-ray photoelectron
Cheryl Brandenburg et al.
Frontiers in cellular neuroscience, 14, 577858-577858 (2020-11-27)
Autism spectrum disorder (ASD) is behaviorally defined and diagnosed by delayed and/or impeded language, stereotyped repetitive behaviors, and difficulties with social interactions. Additionally, there are disruptions in motor processing, which includes the intent to execute movements, interrupted/inhibited action chain sequences

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