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主要文件

安全信息

I9278

Sigma-Aldrich

胰岛素 溶液 人

sterile-filtered, BioXtra, suitable for cell culture

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25 G
¥223.12
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¥582.04

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预计发货时间2025年6月25日详情

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25 G
¥223.12
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About This Item

CAS号:
11061-68-0
MDL编号:
MFCD00131380
UNSPSC代码:
12352209
NACRES:
NA.77

¥223.12

预计发货时间2025年6月25日详情

获取大包装报价

生物来源

Saccharomyces cerevisiae

无菌性

sterile-filtered

产品线

BioXtra

表单

solution

浓度

9.5-11.5 mg/mL

技术

cell culture | mammalian: suitable

杂质

≤50 EU/mL endotoxin

pH值（酸碱度）

7.9-8.5

UniProt登记号

P01308

储存温度

2-8°C

相关类别

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2-氨基嘧啶

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Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

mp

122-126 °C (lit.)

mp

54-58 °C (lit.)

mp

122-126 °C (lit.)

mp

65-70 °C

form

powder

form

crystals

form

-

form

solid

一般描述

胰岛素是由胰岛β-细胞分泌的双链多肽激素。其分子量为~5800 Da。α链和β链是由两个链间二硫键所连接的。α链含有一个链间二硫键。

应用

人胰岛素溶液可作为添加剂用于Dulbecco′改良eagle′培养基(DMEM)培养上皮细胞系和人子宮內膜细胞系，用于最低必需培养基培养人乳腺癌细胞系，用于培养基199培养正常卵巢细胞系。
人胰岛素溶液用于细胞培养的浓度建议为0.5-1 mL/L培养基。
人胰岛素溶液可用于小鼠和大鼠的胰岛素耐受试验。[1][2]它还可用于人胚胎干细胞（hESC）的体外培养和hMSC（人间充质基质细胞）的成脂分化。[3][4]

生化/生理作用

胰岛素在各种细胞过程中起作用，包括促进细胞生长、调节细胞周期、促进葡萄糖摄取。常用作哺乳动物细胞无血清培养基的蛋白添加剂，促进并维持哺乳动物细胞的最优生长。

其他说明

InChI：1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134+,135+,136+,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1

外形

2-8 °C保存

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

胰岛素激素类产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000396609
    0000396607
    0000396607
    0000396609
    0000341617

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    1. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    2. How do I get lot-specific information or a Certificate of Analysis?

      The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    3. What is the concentration of Product I9278, Insulin solution human?

      The acceptable concentration range of this insulin solution can be found on the specification sheet. The lot-specific result is reported on the Certificate of Analysis.

    4. What is the molarity of Product I9278, Insulin solution human?

      A 10mg/mL solution of human insulin has a molarity of 1.7 μmol/mL or 1.7 mM, using the molecular weight of 5807.

    5. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    6. What is the Department of Transportation shipping information for this product?

      Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

    7. My question is not addressed here, how can I contact Technical Service for assistance?

      Ask a Scientist here.

    E Comisso et al.
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    Farinaz Ghodrati et al.
    Scientific reports, 8(1), 8654-8654 (2018-06-07)
    At times, it can be difficult to discern if a lack of overlap in reported interactions for a protein-of-interest reflects differences in methodology or biology. In such instances, systematic analyses of protein-protein networks across diverse paradigms can provide valuable insights.
    Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum System.
    Jones M et al.
    Cytotherapy, 15, 1323-1323 (2013)
    Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.
    Nunes S, et al.
    Cardiovascular Diabetology, 12, 44-44 (2013)
    Hui-Yu Liu et al.
    The Journal of biological chemistry, 284(40), 27090-27100 (2009-08-06)
    Subjects with type 1 diabetes mellitus (T1DM) eventually develop insulin resistance and other features of T2DM such as cardiovascular disorders. The exact mechanism has been not been completely understood. In this study, we tested the hypothesis that excessive or inappropriate
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