跳转至内容

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
所有图片(1)

主要文件

I8250

Sigma-Aldrich

3-碘- L -酪氨酸

别名:

3-单碘- L -酪氨酸

登录查看公司和协议定价

选择尺寸

1 L
¥727.65

¥727.65


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

选择尺寸

变更视图
1 L
¥727.65

About This Item

线性分子式:
IC6H3-4-(OH)CH2CH(NH2)CO2H
CAS号:
分子量:
307.09
Beilstein:
2941266
EC 号:
MDL编号:
UNSPSC代码:
12352200
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.32

¥727.65


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

质量水平

杂质

~5% tyrosine

mp

210 °C (dec.) (lit.)

溶解性

dilute aqueous acid: soluble

储存温度

−20°C

SMILES字符串

N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O

InChI

1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1

InChI key

UQTZMGFTRHFAAM-ZETCQYMHSA-N

基因信息

human ... TH(7054)

正在寻找类似产品? 访问 产品对比指南

相关类别

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
24425277234311413
concentration

0.01 M HClO4 in water (0.01N)

concentration

-

concentration

≥60% (T)

concentration

60%

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

ion chromatography: suitable

technique(s)

toxicology assay: suitable

technique(s)

-

technique(s)

-

一般描述

与二碘酪氨酸偶联的碘酪氨酸可合成 3,5,3′-三碘甲状腺原氨酸 (T3) 或 3,3′,5′-三碘甲状腺原氨酸 (rT3)。[1]

应用

3-碘-L-酪氨酸已作为酪氨酸羟化酶的抑制剂用于 果蝇 [2] [3] 和蚕蛹。[4]

生化/生理作用

3-碘酪氨酸 (3-IY) 抑制酪氨酸羟化酶,后者催化酪氨酸形成左旋多巴。[3]严重甲减和甲状腺肿时,碘酪氨酸脱碘酶缺乏导致血清和尿中 3-IY 水平升高。[5]
TH(酪氨酸 3-羟化酶)负责催化去甲肾上腺素能生物合成途径的第一步。[6]TH 突变 [7] 与酪氨酸羟化酶缺乏相关,导致诸如婴儿型帕金森综合征和多巴( 多巴胺 )反应性肌张力障碍以及围产期发病的脑病。[8]
酪氨酸羟化酶抑制剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

    没有发现合适的版本?

    如果您需要特殊版本,可通过批号或批次号查找具体证书。

    已有该产品?

    在文件库中查找您最近购买产品的文档。

    访问文档库

    A new brain dopamine-deficient Drosophila and its pharmacological and genetic rescue
    Cichewicz K, et al.
    Genes, Brain, and Behavior, 16(3), 394-403 (2017)
    Anionic iodotyrosine residues are required for iodothyronine synthesis
    De Vijlder JJ and den Hartog MT
    European Journal of Endocrinology, 138(2), 227-231 (1998)
    Dopamine and serotonin are both required for mate-copying in Drosophila melanogaster
    Monier M, et al.
    Frontiers in Behavioral Neuroscience, 12(3), 334-334 (2018)
    Differential regulation of tyrosine hydroxylase in cuticular melanization and innate immunity in the silkworm Bombyx mori
    Lee KS, et al.
    Journal of Asia-Pacific Entomology, 18(4), 765-770 (2015)
    P F Fitzpatrick
    Biochemistry, 30(15), 3658-3662 (1991-04-16)
    The steady-state kinetic mechanism for rat tyrosine hydroxylase has been determined by using recombinant enzyme expressed in insect tissue culture cells. Variation of any two of the three substrates, tyrosine, 6-methyltetrahydropterin, and oxygen, together at nonsaturating concentrations of the third

    我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持