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Merck
CN

I7908

Sigma-Aldrich

白细胞介素-2 人

recombinant, expressed in Pichia pastoris, suitable for cell culture

别名:

IL-2, T细胞生长因子, 白细胞介素-2

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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.75

生物来源

human

质量水平

重组

expressed in Pichia pastoris

检测方案

≥98% (SDS-PAGE and HPLC)

形式

lyophilized powder

分子量

predicted mol wt ~15 kDa

包装

pkg of 10KU

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... IL2(3558)

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应用

人白介素2已用于评估肿瘤坏死因子受体1(TNFR1)的变化。它也已用于Tregs上的TNFR2表达。

生化/生理作用

白介素2(IL2)是一种促炎性细胞因子。它由三个亚基组成,其中β亚基对于受体介导的信号传导很重要。IL2增强T调节细胞的发育,并在抗肿瘤免疫中起关键作用。
白细胞介素-2(IL-2)是由某些T淋巴细胞亚群产生的免疫调节因子。该淋巴因子能够促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖、诱导γ-干扰素和B细胞生长因子分泌中发挥作用,并且能够调节IL-2受体的表达。

外形

从50 mM磷酸钠缓冲盐水(pH值7.0)中的0.2 μm过滤溶液中冻干,每0.1 mL细胞因子含有0.1%人血清白蛋白。

分析说明

在使用IL-2依赖性鼠细胞毒性T细胞系CTLL-2的细胞增殖测定中测试生物活性。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

分析证书(COA)

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