应用
人白介素2已用于评估肿瘤坏死因子受体1(TNFR1)的变化。它也已用于Tregs上的TNFR2表达。
生化/生理作用
白介素2(IL2)是一种促炎性细胞因子。它由三个亚基组成,其中β亚基对于受体介导的信号传导很重要。IL2增强T调节细胞的发育,并在抗肿瘤免疫中起关键作用。
白细胞介素-2(IL-2)是由某些T淋巴细胞亚群产生的免疫调节因子。该淋巴因子能够促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖、诱导γ-干扰素和B细胞生长因子分泌中发挥作用,并且能够调节IL-2受体的表达。
外形
从50 mM磷酸钠缓冲盐水(pH值7.0)中的0.2 μm过滤溶液中冻干,每0.1 mL细胞因子含有0.1%人血清白蛋白。
分析说明
在使用IL-2依赖性鼠细胞毒性T细胞系CTLL-2的细胞增殖测定中测试生物活性。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
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