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Merck
CN

I5396

Sigma-Aldrich

Interleukin-1α from mouse

IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

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别名:
mIL-1α, IL-1α
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.77

生物来源

mouse

质量水平

重组

expressed in E. coli

检测方案

≥97% (SDS-PAGE)

形式

lyophilized powder

效能

3-7 pg/mL ED50

质量

endotoxin tested

分子量

18 kDa

包装

pkg of 5 and 25 μg

技术

cell culture | mammalian: suitable

杂质

<0.1 EU/μg

UniProt登记号

储存温度

−20°C

基因信息

mouse ... IL1A(3552)

生化/生理作用

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LA F), activates T cells and lymphocytes, which then proliferate and secrete Interleukin-2 (IL-2). The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

分析说明

The biological activity is measured in a cel proliferation assay using the murine helper T cell line, D10.G4.1.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
含少量动物源组分生物产品

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Katiria Soto-Díaz et al.
Journal of neurochemistry, 152(6), 697-709 (2019-11-30)
Systemic inflammation can exacerbate symptoms of many neurological diseases. This effect may be facilitated by glial cells of the central nervous system (CNS) that alter their transcriptional responses and up-regulate cytokine and chemokine expression which can, in turn trigger immune
Symons, J.A., et al. et al.
Lymphokines and Interferons, A Practical Approach, 272-272 (1987)

商品

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

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