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Merck
CN

I3901

IL-1α rat

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

rIL-1α, IL-1α, 淋巴细胞激活因子

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
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产品名称

白介素1α 来源于大鼠, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

rat

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

1-10 pg/mL ED50

quality

endotoxin tested

mol wt

~18 kDa

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

≤0.1 EU/μg

UniProt accession no.

storage temp.

−20°C

Quality Level

Gene Information

rat ... Il1a(24493)

Analysis Note

通过使用小鼠辅助T细胞系D10.G4.1刺激细胞增殖的能力来测量重组大鼠IL-1α的生物活性。

Biochem/physiol Actions

白介素-1(IL-1),最初称为淋巴细胞激活因子(LA F),可激活T细胞和淋巴细胞,然后增殖并分泌白介素-2(L-2)。使用鼠细胞系D10S在培养物中检测人IL-1α的增殖活性。

Physical form

从含有0.25 mg牛血清白蛋白的0.2 μm过滤磷酸盐缓冲盐水中冻干。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

含少量动物源组分生物产品
低风险生物材料
常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xuankang Wang et al.
Frontiers in neuroscience, 15, 768262-768262 (2021-11-20)
After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive phenotypes according to their different functions: neurotoxic (A1) astrocytes and neuroprotective (A2) astrocytes. Our previous studies proved that photobiomodulation (PBM) can promote motor function recovery and improve
T Nishida et al.
Journal of biochemistry, 105(3), 351-357 (1989-03-01)
A cDNA sequence coding for rat interleukin-1 alpha (IL-1 alpha) has been isolated from a cDNA library that was prepared with mRNA derived from LPS-stimulated rat peritoneal macrophages by using human IL-1 alpha cDNA as a probe. The rat cDNA
Xuankang Wang et al.
Journal of neuroinflammation, 18(1), 256-256 (2021-11-07)
Neurotoxic microglia and astrocytes begin to activate and participate in pathological processes after spinal cord injury (SCI), subsequently causing severe secondary damage and affecting tissue repair. We have previously reported that photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation
Sualyneth Galarza et al.
Advanced healthcare materials, 9(4), e1901419-e1901419 (2020-01-17)
Bioengineers have designed numerous instructive brain extracellular matrix (ECM) environments with tailored and tunable protein compositions and biomechanical properties in vitro to study astrocyte reactivity during trauma and inflammation. However, a major limitation of both protein-based and synthetic model microenvironments
Shuqi Jiang et al.
Journal of inflammation research, 14, 5919-5937 (2021-11-23)
Astrocyte A1/A2 phenotypes may play differential role in the pathogenesis of periventricular white matter (PWM) damage in septic postnatal rats. This study aimed to determine whether melatonin (MEL) would improve the axonal hypomyelination through shifting A1 astrocytes towards A2. One-day-old

商品

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

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