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生物来源
human
质量水平
重组
expressed in E. coli
检测方案
≥97% (SDS-PAGE)
形式
lyophilized powder
效能
0.2-2.0 ng/mL ED50/EC50
质量
endotoxin tested
分子量
26 kDa
包装
pkg of 10 and 50 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
杂质
≤1.000 EU/μg
颜色
white
UniProt登记号
储存温度
−20°C
基因信息
human ... IL6(3569)
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相关类别
生化/生理作用
白细胞介素-6 (IL-6) 是最初在双链 RNA 刺激的细胞培养基中发现的一种多功能蛋白。IL-6 似乎直接参与了感染和损伤后发生的反应，并可能证明在调节急性期反应方面与 IL-1 和 TNF-α 同样重要。据报道，IL-6 由成纤维细胞、活化的 T 细胞、活化的单核细胞或巨噬细胞以及内皮细胞产生。作用于多种细胞，包括成纤维细胞、髓系祖细胞、T 细胞、B 细胞和肝细胞。如许多同义词所示，IL-6 诱导多种效应：浆细胞瘤生长因子 (PCT-GF)、干扰素-β-2（IFN-β 2 ）、单核细胞来源的人 B 细胞生长因子、B 细胞刺激因子 (BSF-2)、肝细胞刺激因子 (HSF)、白细胞介素杂交瘤/浆细胞瘤-1 (IL-HP1)。此外，IL-6 似乎在 T 淋巴细胞增殖中与 IL-2 相互作用。IL-6 还可增强 IL-3 对多潜能造血祖细胞的增殖作用。
外形
从含有 500 μg 牛血清白蛋白的 0.2 μm 磷酸盐缓冲液 (PBS) (pH 7.4) 过滤溶液冻干。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
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商品
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
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