I1145
Interleukin-5 from mouse
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
别名:
IL-5
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关于此项目
biological source
mouse
Quality Level
recombinant
expressed in baculovirus infected Sf21 cells
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
0.04-0.30 ng/mL EC50
mol wt
45-50 kDa
packaging
pkg of 5 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Il5(16191)
Biochem/physiol Actions
Exhibits activity on eosinophils, B cells, and thymocytes.
Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
相关内容
Datasheet
Yuan Wang et al.
Journal of immunology (Baltimore, Md. : 1950), 195(3), 1171-1181 (2015-06-28)
Complement is implicated in asthma pathogenesis, but its mechanism of action in this disease remains incompletely understood. In this study, we investigated the role of properdin (P), a positive alternative pathway complement regulator, in allergen-induced airway inflammation. Allergen challenge stimulated
Stefan Rebhandl et al.
European journal of immunology, 44(7), 2175-2187 (2014-03-29)
Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells. Due to off-target activity, AID is implicated in lymphoma development by introducing genome-wide DNA damage and initiating chromosomal
Xiang Zhu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G974-G982 (2014-04-20)
Extracellular acidification has been observed in allergic inflammatory diseases. Recently, we demonstrated that the proton-sensing receptor G protein-coupled receptor 65 (GPR65) regulates eosinophil survival in an acidic environment in vitro and eosinophil accumulation in an allergic lung inflammation model. For
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I1145-5UG | 04061833847497 |