形式
solid
颜色
white
溶解性
H2O: soluble (Solutions may be stored for several days at 4°C.)
ethanol: moderately soluble (Solutions may be stored for several days at 4°C.)
SMILES字符串
CN1C(=O)N(C)c2ncn(CCO)c2C1=O
InChI
1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3
InChI key
NWPRCRWQMGIBOT-UHFFFAOYSA-N
基因信息
human ... ADORA2B(136)
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应用
Useful synthetic intermediate in the preparation of 7-substituted xanthines.
生化/生理作用
Pharmacological profile similar to theophylline.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
R Pohloudek-Fabini et al.
Die Pharmazie, 39(1), 24-26 (1984-01-01)
The testing of oxyethyltheophylline solutions for injection involved the separate study of their constituents, theophylline and ethophylline, particular attention being given to the behaviour of both these active agents under thermal stress in acid or alkaline medium. Acids exert little
A Apicella et al.
Biomaterials, 14(2), 83-90 (1993-01-01)
An interpretation of the drug release from monolithic water-swellable and soluble polymer tablets is presented. A convenient parameter, alpha, which compares the drug-diffusive conductance in the gel layer with the swelling and dissolving characteristics of the unpenetrated polymer was used
Susruta Majumdar et al.
AAPS PharmSciTech, 13(3), 853-862 (2012-06-01)
Two different types of derivatives of theophylline (Th-H) incorporating ethyleneoxy groups into the promoiety have been synthesized. One is a soft alkyl type where N-methyl-N-methoxyethyleneoxycarbonylaminomethyl chlorides have been used to alkylate Th-H in the 7 position. The other is in
E Hashimoto et al.
Biochemical and biophysical research communications, 204(1), 318-324 (1994-10-14)
Adenosine induced by hypoxia exerts various effects via different types of receptors. Recently, hypoxia was shown to be a strong inducer of vascular endothelial growth factor, a secreted endothelial cell specific mitogen. In this report, we studied on effects of
Binding of theophylline, ethophylline and diprophylline to human serum albumin.
M V Alvarez et al.
Il Farmaco; edizione pratica, 43(7-8), 259-265 (1988-07-01)
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