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安全信息

H7379

Sigma-Aldrich

血红蛋白 人

lyophilized powder

别名:

HB

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About This Item

CAS号:
9008-02-0
MDL编号:
MFCD00131282
UNSPSC代码:
12352202
eCl@ss:
42030116
NACRES:
NA.61

生物来源

human

质量水平

200

表单

lyophilized powder

技术

enzyme immunoassay: suitable

杂质

HIV and hepatitis B antigen, tested negative

溶解性

H2O: soluble 20 mg/mL

UniProt登记号

P02008
P02042
P02100
P09105
P68871
P69891
P69892
P69905

储存温度

2-8°C

基因信息

human ... HBA1(3039) , HBA2(3040) , HBB(3043) , HBD(3045) , HBE1(3046) , HBG1(3047) , HBG2(3048) , HBQ1(3049) , HBZ(3050)

一般描述

血红蛋白是红细胞的主要成分，也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34％。由于它能够将氧从肺部输送到身体组织，促进二氧化碳的返回转运，因此血红蛋白是脊椎动物最重要的呼吸蛋白。

应用

血红蛋白被用于开发检测视黄醇结合蛋白的快速酶免疫分析法。它也被内皮源性舒张因子用于抑制人血小板反应性。

生化/生理作用

Fe2+/Fe3+平衡是血液氧合的生理指标。脱氧血红蛋白通过将亚硝酸盐还原为NO（一种血管舒张剂，可促进血液流向缺氧组织）来辅助反馈回路。
氧气转运蛋白，NO清除剂

注意

由于天然血红蛋白在空气中容易氧化，因此这些制剂可能主要是高铁血红蛋白。

免责声明

仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000422299
0000422298
0000422298
0000422299
0000413906

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. Is Product H7379, Hemoglobin human, methemoglobin?

    Yes. The iron in hemoglobin will oxidize by exposure to air unless special handling and packaging is used.  Because this product is exposed to air during purification and packaging, it will be predominantly methemoglobin.

  4. How can Product H7379, Hemoglobin human, be reduced?

    A procedure for reduction of methemoglobin may be found in the product sheet.

  5. How many donors are used to make a batch of Product H7379, Hemoglobin human?

    This will vary with the batch size, but may come from as many as several hundred donors. All donors are tested and found negative for antibodies to HIV-1/HIV-2, HCV, for HBSAG, and for syphilis.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Chromatograms

application for HPLC

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