所有图片(3)
别名:
11β,17α,21-三羟基-4-孕烯-3,20-二酮 21-乙酸酯, 17-α-羟基皮质甾酮乙酸酯, 17-羟基皮质甾酮 21-乙酸酯, 21-乙酰氧基-4-孕烯-11β,17α-二醇-3,20-二酮, 4-孕烯-11β,17α,21-三醇-3,20-二酮 21-乙酸酯
经验公式（希尔记法）:
C23H32O6
CAS号:
分子量:
404.50
Beilstein:
2066841
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
无菌性
non-sterile
质量水平
检测方案
≥98% (HPLC)
形式
powder
技术
permeability assay: suitable
mp
223 °C (dec.) (lit.)
运输
ambient
储存温度
room temp
SMILES字符串
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
InChI
1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
InChI key
ALEXXDVDDISNDU-JZYPGELDSA-N
基因信息
human ... NR3C1(2908) , SERPINA6(866)
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一般描述
Hydrocortisone 21-acetate is an adrenocortical steroid. Hydrocortisone acts as an immunosuppressive drug and might suppress systemic inflammatory responses. It is used to treat rheumatoid arthritis and adrenal insufficiency. It also functions as an antiallergic agent.
警示用语：
Danger
危险声明
危险分类
Repr. 1B - STOT RE 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Principles of Orthomolecularism, 20-26 (2004)
The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies, 20-26 (2014)
Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production
Attur MG, et al.
Inflammation Research, 49(1), 20-26 (2000)
Holger P Behrsing et al.
Toxicological sciences : an official journal of the Society of Toxicology, 131(2), 470-479 (2012-11-13)
The anticancer drug (2-[4-amino-3-methylphenyl]-5-fluorobenzothiazole lysylamide dihydrochloride) (NSC 710305, Phortress) is a metabolically activated prodrug that causes DNA adduct formation and subsequent toxicity. Preclinically, it was found that hepatic, bone marrow, and pulmonary toxicity presented challenges to developing this drug. An
Adrenal insufficiency in patients with cirrhosis and septic shock: effect of treatment with hydrocortisone on survival
Fernandez J, et al.
Hepatology, 44(5), 1288-1295 (2006)
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