跳转至内容
Merck
CN

H2915

Sigma-Aldrich

HCK (230-497), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

JTK9

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

重组

expressed in baculovirus infected Sf9 cells

质量水平

产品线

PRECISIO® Kinase

方案

≥70% (SDS-PAGE)

表单

buffered aqueous glycerol solution

比活

156-212 nmol/min·mg

分子量

~57 kDa

UniProt登记号

相关疾病

cancer (leukemia)

运输

dry ice

储存温度

−70°C

基因信息

human ... HCK(3055)

一般描述

HCK (hematopoietic cell kinase), a protein-tyrosine kinase belonging to the Src family, is expressed in certain hemopoietic cells. It is especially prominent in cells of myeloid lineage, particularly mature granulocytes and monocytes.

生化/生理作用

HCK (hematopoietic cell kinase) gene is mapped to human chromosome 20q11-q12. This region on the chromosome urdergoes interstitial deletions in some acute myeloid leukemias and myeloproliferative disorders, thereby suggesting HCK participation in the pathogenesis of these conditions.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助,请联系 客户支持

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

S F Ziegler et al.
Molecular and cellular biology, 7(6), 2276-2285 (1987-06-01)
Protein-tyrosine kinases are implicated in the control of cell growth by virtue of their frequent appearance as products of retroviral oncogenes and as components of growth factor receptors. Here we report the characterization of a novel human protein-tyrosine kinase gene
N Quintrell et al.
Molecular and cellular biology, 7(6), 2267-2275 (1987-06-01)
We have isolated cDNAs representing a previously unrecognized human gene that apparently encodes a protein-tyrosine kinase. We have designated the gene as HCK (hemopoietic cell kinase) because its expression is prominent in the lymphoid and myeloid lineages of hemopoiesis. Expression

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门