推荐产品
生物来源
human
质量水平
方案
97-100% (agarose gel electrophoresis)
表单
lyophilized powder
技术
immunofluorescence: suitable
适用性
suitable for electrophoresis and chromatography standard
UniProt登记号
储存温度
−20°C
基因信息
human ... HBA2(3040)
一般描述
血红蛋白A2(HBA2)定位于人染色体16p13.3上。 HBA2是一种少量的血红蛋白成分,包含两条α 和δ 链。
血红蛋白是红细胞的主要成分,也是其表现为红色的原因。其在红细胞中的正常浓度为34%。由于它能够将氧从肺部输送到身体组织,并促进二氧化碳的返回运输,因此血红蛋白是脊椎动物最重要的呼吸蛋白。
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).
应用
亚铁稳定的人血红蛋白A2已被用作反相高效液相色谱中的参考品,可用于对δ -珠蛋白洗脱曲线进行定量。 它还被用作同位素稀释质谱(IDMS)测量的校准试剂。
血红蛋白A2可用于通过时间分辨免疫荧光测定法对胎儿血红蛋白进行测定。
生化/生理作用
在β-地中海贫血性状患者中观察到血红蛋白A2(HBA2)的水平升高。
包装
包装尺寸表示通过Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).所报道方法测定的血红蛋白量。
重悬
当用缓冲液进行溶解时,可得到> 90%的铁血红蛋白。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Elevated hemoglobin A2 as a marker for beta-thalassemia trait in pregnant women
The Tohoku Journal of Experimental Medicine, 223(3), 223-226 (2011)
JPMA. The Journal of the Pakistan Medical Association, 62(12), 1314-1317 (2013-07-23)
To screen immediate family members of thalassaemia patients for carrier identification and counselling. The cross-sectional study was conducted at an urban thalassaemia treatment and prevention centre in Karachi, Pakistan, from January to December 2008, and involved 188 siblings of 100
Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies
Human Gene Therapy Methods, 29(1), 60-74 (2018)
Pediatric hematology and oncology, 29(5), 472-478 (2012-08-08)
Iron deficiency (IDA) and beta thalassemia trait (TT) are the most common causes of hypochromia and microcytosis. Many indices have been defined to quickly discriminate these similar entities via parameters obtained from automated blood cell analyzers. However, studies in the
Haemoglobin A₂ analysis.
International journal of laboratory hematology, 35(1), 116-116 (2012-11-20)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门