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主要文件

G8877

Sigma-Aldrich

鸟苷5′-三磷酸 钠盐 水合物

≥95% (HPLC), powder

别名:

GTP

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25 G
¥2,465.37
500 G
¥10,505.95

¥2,465.37


国内现货,预计发货时间2025年4月27日详情


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25 G
¥2,465.37
500 G
¥10,505.95

About This Item

经验公式(希尔记法):
C10H16N5O14P3 · xNa+
CAS号:
分子量:
523.18 (free acid basis)
Beilstein:
3585677
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.77

¥2,465.37


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

质量水平

方案

≥95% (HPLC)

表单

powder

颜色

white

溶解性

H2O: 50 mg/mL

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1

InChI key

KZRMTEVIDYXWQW-CYCLDIHTSA-K

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D15292780352513259
Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

grade

battery grade

grade

-

grade

-

grade

analytical standard

form

liquid

form

liquid

form

liquid

form

-

application(s)

battery manufacturing

application(s)

-

application(s)

-

application(s)

environmental
pharmaceutical

impurities

≤10 ppm H2O, ≤10 ppm acid

impurities

-

impurities

-

impurities

≤0.02% water

assay

≥99.9%

assay

99%

assay

≥99.0% (GC)

assay

≥99.0% (GC)

应用

鸟苷5′-三磷酸钠盐水合物已用于:
  • 辣根过氧化物酶(HRP)修饰的平板试剂制备[1]
  • 全细胞电压钳记录[2]
  • 转谷氨酰胺酶(tTG)的体外抑制[3]

生化/生理作用

GTP可用作参与到将化学能导入至特定的生物合成途径的磷酸酶和焦磷酸酶载体。GTP可将参与到包括增殖、分化等多种细胞过程的信号转导G蛋白进行激活,以及多种细胞间激酶级联反应的激活。增殖和凋亡是部分受到由小GTPase Ras和Rho介导的GTP水解调控的。另一种类型的小GTPase,Rab可在囊泡的对接和融合中起到作用,并也可能参与到囊泡的形成。除了在信号转导中发挥作用外,GTP还可在DNA和RNA的酶促生物合成中作为单核苷酸单位的富含能量前体。

特点和优势

该化合物是环状核苷酸研究的特色产品。点击此处以发现更多的环状核苷酸特色产品。可访问sigma.com/discover-bsm了解更多关于用于其他研究领域生物活性小分子。

制备说明

由5′-GMP的酶促磷酸化而制备。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type N95 (US)

  • 技术规格说明书

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    实验方案

    HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

    ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

    HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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