product name
甘氨酸, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%
生物来源
non-animal source
质量水平
Agency
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications
检测方案
≥98.5%
形式
powder
质量
meets EP, JP, USP testing specifications
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
white
pH值(酸碱度)
5.9-6.4
pKa (25 °C)
(1) 2.35, (2) 9.60
2.35
mp
240 °C (dec.) (lit.)
溶解性
H2O: 100 mg/mL
SMILES字符串
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
基因信息
rat ... Grin2a(24409)
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应用
氨基酸可用于细胞培养基的研发以及现有培养基的配制。
生化/生理作用
脊髓中的抑制性神经递质,NMDA受体的变构调节器。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Brain structure & function, 220(5), 2639-2652 (2014-06-30)
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Human molecular genetics, 24(5), 1420-1431 (2014-11-16)
Giant axonal neuropathy (GAN) is a progressive neurodegenerative disease caused by autosomal recessive mutations in the GAN gene resulting in a loss of a ubiquitously expressed protein, gigaxonin. Gene replacement therapy is a promising strategy for treatment of the disease;
Biochimica et biophysica acta, 1853(9), 2104-2114 (2015-03-15)
Bax inhibitor-1 (BI-1) is an evolutionarily conserved pH-dependent Ca²⁺ leak channel in the endoplasmic reticulum and the founding member of a family of six highly hydrophobic mammalian proteins named transmembrane BAX inhibitor motif containing (TMBIM) 1-6 with BI-1 being TMBIM6.
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