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Merck
CN

G5417

SAFC

甘氨酸

制药生产

别名:

氨基乙酸, 甘氨酸

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About This Item

线性分子式:
NH2CH2COOH
CAS号:
分子量:
75.07
Beilstein:
635782
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
NACRES:
NA.25

生物来源

non-animal source

质量水平

检测方案

≥98.5%

形式

crystalline powder

技术

cell culture | mammalian: suitable

杂质

endotoxin, heavy metals, trace metals, residual solvents, tested

pH值(酸碱度)

5.9-6.4

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

H2O: 100 mg/mL

紫外吸收

λ: 260 nm Amax: ≤0.04
λ: 260 nm Amax: -0.006
λ: 280 nm Amax: ≤0.04
λ: 280 nm Amax: -0.003

适用性

suitable for manufacturing use

应用

pharmaceutical (small molecule)

异质活性

cytotoxicity, tested

SMILES字符串

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

基因信息

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一般描述

我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity Program规定的要求。

M-Clarity Program

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料,而且帮助他们更快地将产品投放市场并简化监管问题。请相信我们能够为您带来透明的供应链和可靠的全球采购能力,以最佳的法规支持和服务简化您的产品认证。
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应用

甘氨酸是一种非必需氨基酸。 它是最简单的氨基酸,在生物学中具有多种作用。 在生物氨基酸中,甘氨酸结构的独特之处在于它不具有不对称中心,因此不是手性的。 它常被用作细胞培养基成分,用于治疗性重组蛋白和单克隆抗体的商业化生物制造。

生化/生理作用

脊髓中的抑制性神经递质,NMDA受体的变构调节器。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)


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