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Merck
CN

G1501

L-谷氨酸 钾盐 一水合物

≥99% (HPLC), powder

别名:

2-氨基-5-羟基-5-氧基戊酸钾, MPG, 谷氨酸单钾, (S)-2-氨基戊二酸, L-α-氨基戊二酸 钾盐, L-2-氨基戊二酸 钾盐, L-谷氨酸钾, Glu

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关于此项目

经验公式（希尔记法）:
C5H8KNO4 · H2O
化学文摘社编号:
6382-01-0
分子量:
203.23
MDL number:
MFCD00150343
UNSPSC Code:
12352209
PubChem Substance ID:
24895063
NACRES:
NA.32
Beilstein/REAXYS Number:
3637377

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产品名称

L-谷氨酸 钾盐 一水合物, ≥99% (HPLC), powder

SMILES string

O.[K+].N[C@@H](CCC([O-])=O)C(O)=O

InChI

1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1

InChI key

XIBUKSQTWSKJMQ-QTNFYWBSSA-M

assay

≥99% (HPLC)

form

powder

color

white

Quality Level

300

Gene Information

human ... GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... GRIK1(14805), GRIK2(14806), GRIK3(14807), GRIK4(110637), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... GRIK1(29559), GRIK2(54257), GRIK3(298521), GRIK4(24406), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

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相关类别

General description

L-谷氨酸是哺乳动物中枢神经系统（CNS）中主要的兴奋性神经递质。它与膜结合的谷氨酸受体相互作用。在细胞培养中，谷氨酸钾也被用作MEM非必需氨基酸溶液的组成部分。

Features and Benefits

我们高纯度的L-谷氨酸钾盐一水合物将为您的纯化或制备神经病理疾病的研究需要提供支持

Application

使用L-谷氨酸钾盐一水合物
  • 在细胞培养中，MEM非必需氨基酸溶液的组成部分。
  • 用于纯化牛脑的微管蛋白。
  • 用于在形成双色极性标记荧光微管种子时在原液中制备淬火缓冲液。
  • 从大肠杆菌菌株制备RF2（释放因子2）无细胞抽出物。
  • 拟南芥植物培养期间制备原液。

Biochem/physiol Actions

L-谷氨酸在发育、学习、记忆、可塑性和认知中起着关键作用。它在神经病理学疾病的发病机制中起着至关重要的作用，例如癫痫、精神分裂症、中风、缺血、肌萎缩侧索硬化症（amyotrophic lateral sclerosis），、廷顿舞蹈病和帕金森病。谷氨酸还负责长时程增强（LTP）和长时程抑郁（LTD）的激活。谷氨酸受体的诱导在偏头痛的病理生理学中起着关键作用。
红藻氨酸、NMDA和使君子氨酸受体的激动剂；兴奋性氨基酸神经递质。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000523080
0000523080
0000519799
0000519797
0000519798

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