G110
胍那苄 乙酸盐
α2 adrenoceptor agonist, powder
别名:
1-(2,6-二氯亚苄基氨基)胍 乙酸盐, WY-8678
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关于此项目
经验公式（希尔记法）:
C8H8Cl2N4 · C2H4O2
化学文摘社编号:
分子量:
291.13
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
245-534-7
MDL number:
Form:
powder
Quality level:
产品名称
胍那苄 乙酸盐, powder
form
powder
Quality Level
color
white
solubility
H2O: 10 mg/mL, alcohol: 50 mg/mL
originator
Wyeth
SMILES string
CC(O)=O.NC(=N)N\N=C\c1c(Cl)cccc1Cl
InChI
1S/C8H8Cl2N4.C2H4O2/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12;1-2(3)4/h1-4H,(H4,11,12,14);1H3,(H,3,4)/b13-4+;
InChI key
MCSPBPXATWBACD-GAYQJXMFSA-N
Gene Information
human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
商品
Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.
DISCOVER Bioactive Small Molecules for Neuroscience
Déborah Tribouillard-Tanvier et al.
PloS one, 3(4), e1981-e1981 (2008-04-24)
Prion-based diseases are incurable transmissible neurodegenerative disorders affecting animals and humans. Here we report the discovery of the in vivo antiprion activity of Guanabenz (GA), an agonist of alpha2-adrenergic receptors routinely used in human medicine as an antihypertensive drug. We
Melissa J Fullwood et al.
Progress in molecular biology and translational science, 106, 75-106 (2012-02-22)
The unfolded protein response, also known as endoplasmic reticulum (ER) stress, has been implicated in numerous human diseases, including atherosclerosis, cancer, diabetes, and neurodegenerative disorders. Protein misfolding activates one or more of the three ER transmembrane sensors to initiate a
B Holmes et al.
Drugs, 26(3), 212-229 (1983-09-01)
Guanabenz is an orally active central alpha 2-adrenoceptor agonist. Its antihypertensive action is thought to result from a decrease in sympathetic outflow from the brain to the peripheral circulatory system as a result of stimulation of central alpha 2-adrenoceptors. In
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G110-100MG | 04061832090948 |
| G110-500MG | 04061832090962 |
| G110-25MG | 04061833625033 |