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文件

F9397

Sigma-Aldrich

氟他胺

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别名:
2-甲基-N-[4-硝基-3-（三氟甲基）苯基]丙酰胺
经验公式（希尔记法）:
C11H11F3N2O3
CAS号:
13311-84-7
分子量:
276.21
EC 号:
236-341-9
MDL编号:
MFCD00072009
UNSPSC代码:
51111800
PubChem化学物质编号:
24278446
NACRES:
NA.77

质量水平

100

创始人

Schering Plough

SMILES字符串

CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI

1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)

InChI key

MKXKFYHWDHIYRV-UHFFFAOYSA-N

基因信息

human ... AR(367)
mouse ... Ar(11835)
rat ... Ar(24208)

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应用

氟他胺已被用于考察睾丸素对胶质细胞源性神经营养因子（Gdnf）mRNA的体外生产的影响。它还被用于研究氟他胺对肛门生殖器距离和乳头保留的影响。

生化/生理作用

氟他胺是一种非甾体抗雄激素药。它包括硝基芳香结构。氟他胺是睾丸素和二氢睾丸素受体的强效竞争剂。它是一种强效的肝毒素。

特点和优势

该化合物由Schering Plough开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2 - STOT RE 2

靶器官

Liver

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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