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![N-[3-(2-呋喃基)丙烯酰基]-亮氨酸-甘氨酸-脯氨酸-丙氨酸](/deepweb/assets/sigmaaldrich/product/structures/805/876/96b5fb57-71c8-4c6b-b5d2-fafe7374cd85/640/96b5fb57-71c8-4c6b-b5d2-fafe7374cd85.png)
产品名称
N- [3-（2-呋喃基）丙烯酰基]-Phe - 双甘氨酸,
质量水平
储存温度
−20°C
SMILES字符串
OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2
InChI
1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1
InChI key
ZDLZKMDMBBMJLI-FDMDGMSGSA-N
基因信息
human ... ACE(1636) , ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421) , ACE2(70008) , ACE3(498012)
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Amino Acid Sequence
FA-Phe-Gly-Gly
一般描述
N-[3-（2-呋喃基）丙烯酰基]-Phe-Gly-Gly 作为血管紧张素转化酶 (ACE) 的底物，用于 ACE 的抑制试验。
应用
N-[3-（2-呋喃基）丙烯酰基] 苯基-Gly-Gly 已用于 ACE（血管紧张素转化酶）抑制活性的动力学分光光度法测定。
底物
连续分光光度法测定血管紧张素转化酶 (ACE) 的底物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Zhen-Hao Li et al.
Scientific reports, 7(1), 12243-12243 (2017-09-28)
Quality control is critical for ensuring the safety and effectiveness of drugs. Current quality control method for botanical drugs is mainly based on chemical testing. However, chemical testing alone may not be sufficient as it may not capture all constituents
E Villard et al.
American journal of human genetics, 58(6), 1268-1278 (1996-06-01)
Plasma angiotensin I-converting enzyme (ACE) levels are highly genetically determined. A previous segregation-linkage analysis suggested the existence of a functional mutation located within or close to the ACE locus, in almost complete linkage desequilibrium (LD) with the ACE insertion/deletion (I/D)
Anees A Syed et al.
Journal of ethnopharmacology, 193, 555-565 (2016-10-11)
Ulmus wallichiana Planchon (Himalayan Elm), a traditional medicinal plant, used in fracture healing in folk tradition of Uttarakhand, Himalaya, India. It is also used as diuretic. U. rhynchophylla, native to China, known as Gou Teng in Chinese medicine, is used
Siqi Sun et al.
Marine drugs, 17(3) (2019-03-22)
Angiotensin I-converting enzyme (ACE) inhibitory peptides derived from seaweed represent a potential source of new antihypertensive. The aim of this study was to isolate and purify ACE inhibitory peptides (ACEIPs) from the protein hydrolysate of the marine macroalga Ulva intestinalis.
T P Gorski et al.
Clinical chemistry, 37(8), 1390-1393 (1991-08-01)
For normal and above-normal concentrations of angiotensin-converting enzyme (ACE; EC 3.4.15.1) activity in plasma, results of a manual fluorometric method [with hippuryl-histidyl-leucine (HHL), 5 mmol/L, as substrate] correlated well with those of an automated spectrophotometric method [with 3-(2-furylacryloyl)-L-phenylalanyl-glycyl-glycine (FAPGG), 2
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