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Merck
CN

EMU061791

MISSION® esiRNA

targeting mouse Ptpn1

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CGGAACAGGTACCGAGATGTCAGCCCTTTTGACCACAGTCGGATTAAATTGCACCAGGAAGATAATGACTATATCAATGCCAGCTTGATAAAAATGGAAGAAGCCCAGAGGAGCTATATTCTCACCCAGGGCCCTTTACCAAACACATGTGGGCACTTCTGGGAGATGGTGTGGGAGCAGAAGAGCAGGGGCGTGGTCATGCTCAACCGCATCATGGAGAAAGGCTCGTTAAAATGTGCCCAGTATTGGCCACAGCAAGAAGAAAAGGAGATGGTCTTTGATGACACAGGTTTGAAGTTGACACTAATCTCTGAAGATGTCAAGTCATATTACACAGTACGACAGTTGGAGTTGGAAAACCTGACTACCAAGGAGACTCGAGAGATCCTGCCTTTCCACTACACC

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Liza D Morales et al.
PloS one, 9(5), e97104-e97104 (2014-05-09)
To maintain tissue homeostasis, apoptosis is functionally linked to the cell cycle through the retinoblastoma (Rb)/E2F pathway. When the Rb tumor suppressor protein is functionally inactivated, E2F1 elicits an apoptotic response through both intrinsic (caspase-9 mediated) and extrinsic (caspase-8 mediated)
Xiaoyan Zhang et al.
Scientific reports, 5, 12987-12987 (2015-08-12)
Renal mesangial cells (RMCs) constitute a population of cells in glomerular mesangium. Inflammatory cytokines produced by RMCs play a vital role in renal inflammation. miRNAs are key regulators of inflammatory cytokine expression. The abnormal expression of renal miRNAs and the



全球贸易项目编号

货号GTIN
EMU061791-20UG04061828489404
EMU061791-50UG04061828264131