描述
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质量水平
产品线
MISSION®
形式
lyophilized powder
esiRNA cDNA靶序列
CAGCCCTGTTCTTGGACTGTCAGCTGGTATTTGGGCAAAGATATTGTCTTCATTTACTGATAAGGAACTCCATGCTTATGCAAAAGCTGGAGCAGTTGCTGAAGAAGTCTTAGCAGCCATCAGAACTGTGATTGCGTTTGGAGGACAAAAGAAGGAACTTGAAAGGTACAATAACAACTTGGAAGAAGCTAAAAGGCTGGGGATAAAGAAAGCTATCACGGCCAACATCTCCATGGGTGCAGCTTTTCTCCTTATCTATGCATCATATGCTCTGGCATTCTGGTATGGGACTTCCTTGGTCATCTCCAAAGAATACTCTATTGGACAAGTGCTCACTGTCTTCTTTTCCGTGTTAATTGGAGCATTCAGTGTTGGACAGGCATCTCCAAATATTGAAGCCTTCGCCAATGCACGAGGAGCAGCTTATGAAGTCTTCAAAATAATTGATAATAAGCCCAGTATAGACAGCTTCTCAAAGAGTGGGCAC
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... ABCB1A(18671) , Abcb1a(18671)
相关类别
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Nadejda Sigal et al.
Infection and immunity, 83(6), 2358-2368 (2015-04-01)
Human multidrug efflux transporters are known for their ability to extrude antibiotics and toxic compounds out of cells, yet accumulating data indicate they have additional functions in diverse physiological processes not related to drug efflux. Here, we show that the
Patric J Jansson et al.
The Journal of biological chemistry, 290(15), 9588-9603 (2015-02-28)
Multidrug resistance (MDR) is a major obstacle in cancer treatment. More than half of human cancers express multidrug-resistant P-glycoprotein (Pgp), which correlates with a poor prognosis. Intriguingly, through an unknown mechanism, some drugs have greater activity in drug-resistant tumor cells
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