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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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主要文件

安全信息

EHU083501

Sigma-Aldrich

MISSION® esiRNA

targeting human AKT1, RP11-982M15.2

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4 L
CN¥2,156.63

CN¥2,156.63

预计发货时间October 17, 2025详情

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4 L
CN¥2,156.63

About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

CN¥2,156.63

预计发货时间October 17, 2025详情

描述

Powered by Eupheria Biotech

质量水平

100

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

ACAATCCGATTCACGTAGGGAAATGTTAAGGACTTCTGCAGCTATGCGCAATGTGGCATTGGGGGGCCGGGCAGGTCCTGCCCATGTGTCCCCTCACTCTGTCAGCCAGCCGCCCTGGGCTGTCTGTCACCAGCTATCTGTCATCTCTCTGGGGCCCTGGGCCTCAGTTCAACCTGGTGGCACCAGATGCAACCTCACTATGGTATGCTGGCCAGCACCCTCTCCTGGGGGTGGCAGGCACACAGCAGCCCCCCAGCACTAAGGCCGTGTCTCTGAGGACGTCATCGGAGGCTGGGCCCCTGGGATGGGACCAGGGATGGGGGATGGGCCAGGGTTTACCCAGTGGGACAGAGGAGCAAGGTTTAAATTTGTTATTGTGTATTATGTTGTTCAAATGCATTTTGGGGGTTTTTAATCTTTGTGACAGGAAAGCCC

基因组数据库 |人类登记号

ENSG00000142208

NCBI登记号

NM_005163

运输

ambient

储存温度

−20°C

基因信息

human ... AKT1(207) , AKT1(207)

相关类别

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此商品
D6510027099732222
Dichloromethane suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer

439223

Dichloromethane

Dichloromethane contains 40-150 ppm amylene as stabilizer, ACS reagent, ≥99.5%

D65100

Dichloromethane

Dichloromethane anhydrous, ≥99.8%, contains 40-150 ppm amylene as stabilizer

270997

Dichloromethane

Dichloromethane puriss. p.a., ACS reagent, reag. ISO, ≥99.9% (GC)

32222

Dichloromethane

Quality Level

100

Quality Level

100, 200

Quality Level

200

Quality Level

200

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable

technique(s)

-

assay

≥99.9%

assay

≥99.5%

assay

≥99.8%

assay

≥99.9% (GC)

form

liquid

form

liquid

form

liquid

form

liquid

UV absorption

λ: 235 nm Amax: 1.00, λ: 250 nm Amax: 0.05, λ: 340-400 nm Amax: 0.01, λ: 240 nm Amax: 0.20, λ: 260 nm Amax: 0.02

UV absorption

-

UV absorption

-

UV absorption

-

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C), 6.86 psi ( 20 °C)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    LYU
    IXU
    VVU
    JUU
    IPU

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    Gang Shen et al.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 50(2), 798-809 (2018-10-12)
    Bromodomain-containing protein 4 (BRD4) overexpression participates in prostate cancer progression by enhancing the transcriptional activity and expression of several key oncogenes. AZD5153 is a novel BRD4 inhibitor. Prostate cancer cells were treated with AZD5153. Cell survival was tested by MTT
    Farrukh Aqil et al.
    Cancer letters, 449, 186-195 (2019-02-17)
    Gene-silencing with targeted siRNAs has great potential as a therapeutic approach for various diseases including cancer. However, intracellular delivery of siRNA is challenging. We used bovine milk exosomes as a novel system for siRNA delivery. First, we demonstrated that exosomes
    Guoxing Xu et al.
    Scientific reports, 7, 42411-42411 (2017-02-17)
    Recent studies have shown that some members of the tripartite motif-containing protein (TRIM) family serve as important regulators of tumorigenesis. However, the biological role of TRIM14 in osteosarcoma remains to be established. In this study, we showed that TRIM14 is
    Sisi Chen et al.
    Experimental hematology, 45, 74-84 (2016-10-25)
    Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC) transplantation remains limited by the inability to expand functional HSCs ex vivo. To determine the role of phosphoinositide 3-kinase (PI3K)/AKT signaling in human hematopoietic stem and progenitor
    Deepak Bhere et al.
    Scientific reports, 10(1), 1779-1779 (2020-02-06)
    Dysregulation of miRNA expression has been implicated in cancer. Numerous strategies have been explored to modulate miR but sub-optimal delivery and inability to concurrently target multiple pathways involved in tumor progression have limited their efficacy. In this study, we explored
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    商品

    esiRNA Knockdown Efficiency Tested by Western Blotting

    Quantitative and qualitative western blotting to validate knockdown by esiRNA.

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