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EHU042081

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human PRKAA2

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About This Item

UNSPSC代码:

41105324

NACRES:

NA.51

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描述

质量水平

100

产品线

MISSION^®

表单

lyophilized powder

esiRNA cDNA靶序列

GCAGATTCTGTCTGCTGTGGATTACTGTCATAGGCATATGGTTGTTCATCGAGACCTGAAACCAGAGAATGTCCTGTTGGATGCACACATGAATGCCAAGATAGCCGATTTCGGATTATCTAATATGATGTCAGATGGTGAATTTCTGAGAACTAGTTGCGGATCTCCAAATTATGCAGCACCTGAAGTCATCTCAGGCAGATTGTATGCAGGTCCTGAAGTTGATATCTGGAGCTGTGGTGTTATCTTGTATGCTCTTCTTTGTGGCACCCTCCCATTTGATGATGAGCATGTACCTACGTTATTTAAGAAGATCCGAGGGGGTGTCTTTTATATCCCAGAATATCTCAATCGTTCTGTCGCCACTCTCCTGATGCATATGCTGCAGGTTGACCCACTGAAACGA

基因组数据库 |人类登记号

ENSG00000162409

NCBI登记号

NM_006252

运输

ambient

储存温度

−20°C

基因信息

human ... PRKAA2(5563) , PRKAA2(5563)

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此商品	KCQS01	KCQS02	KCQS07
KCQS00 KiCqStart^® SYBR^® Green qPCR ReadyMix预混液^™	KCQS01 KiCqStart^® SYBR^® Green qPCR ReadyMix预混液^™	KCQS02 KiCqStart^® SYBR^® Green qPCR ReadyMix预混液^™	KCQS07 KiCqStart^®一步法探针RT-qPCR ReadyMix^™
technique(s) qPCR: suitable	technique(s) qPCR: suitable	technique(s) qPCR: suitable	technique(s) qPCR: suitable
form liquid	form liquid	form liquid	form liquid
usage sufficient for 1250 reactions	usage sufficient for 1250 reactions, sufficient for 250 reactions, sufficient for 5000 reactions	usage sufficient for 1250 reactions, sufficient for 250 reactions, sufficient for 5000 reactions	usage sufficient for 500 reactions
feature dNTPs included	feature dNTPs included, hotstart	feature dNTPs included, hotstart	feature dNTPs included, hotstart
storage condition protect from light	storage condition protect from light	storage condition protect from light	storage condition protect from light
color colorless	color colorless	color colorless	color light blue

一般描述

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Lot/Batch Number

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Rhynchophylline Attenuates Senescence of Endothelial Progenitor Cells by Enhancing Autophagy.

Lin Lin et al.

Frontiers in pharmacology, 10, 1617-1617 (2020-02-13)

The increase of blood pressure accelerates endothelial progenitor cells (EPCs) senescence, hence a significant reduction in the number of EPCs is common in patients with hypertension. Autophagy is a defense and stress regulation mechanism to assist cell homeostasis and organelle

AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation.

Meera Saxena et al.

Journal of cell science, 131(14) (2018-06-29)

The developmental programme of epithelial-mesenchymal transition (EMT), involving loss of epithelial and acquisition of mesenchymal properties, plays an important role in the invasion-metastasis cascade of cancer cells. In the present study, we show that activation of AMP-activated protein kinase (AMPK)

Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade.

Wei-Wen Su et al.

International journal of medical sciences, 17(5), 678-684 (2020-03-27)

Background: Adenine exhibits potential anticancer activity against several types of malignancies. However, whether adenine has anticancer effects on hepatocellular carcinoma (HCC) cells is incompletely explored. Methods: Human HCC cell lines HepG2 and SK-Hep-1 (p53-wild type) and Hep3B (p53-deficient) were used

Metabolic reprogramming and AMPKα1 pathway activation by caulerpin in colorectal cancer cells.

Hua Yu et al.

International journal of oncology, 50(1), 161-172 (2016-12-07)

Caulerpin, a secondary metabolite from the marine invasive green algae Caulerpa cylindracea is known to induce mitochondrial dysfunctions. In this study, the anticancer property of caulerpin was assessed in a panel of colorectal cancer cell lines. We demonstrated that caulerpin

Angiotensin II Receptor Type 1 Antagonists Modulate Vascular Smooth Muscle Cell Proliferation and Migration via AMPK/mTOR.

Yingshuai Zhao et al.

Cardiology, 143(1), 1-10 (2019-07-16)

The aberrant proliferation and migration of vascular smooth muscle cells (VSMCs) in the vascular wall are crucial pathological events involved in cardiovascular impairments including hypertension, heart failure, and atherosclerosis. At the molecular level, the mammalian target of rapamycin (mTOR)-ribosomal protein

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安全信息

MISSION^® esiRNA