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E006

EDDP 高氯酸盐

Name: EDDP 高氯酸盐
Brand: SIGMA

Benzodiazepine receptor inverse agonist, solid

别名:

β-CCA methylamide, FG-7142, N-Methyl-β-carboline-3-carboxamide

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关于此项目

经验公式（希尔记法）:

C₁₃H₁₁N₃O

化学文摘社编号:

78538-74-6

分子量:

225.25

UNSPSC Code:

12352106

PubChem Substance ID:

24278181

NACRES:

NA.77

MDL number:

MFCD00055075

Form:

solid

Quality level:

100

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属性

产品名称

EDDP 高氯酸盐,

form

solid

Quality Level

100

color

light tan

solubility

DMSO: >10 mg/mL, H₂O: insoluble

SMILES string

CNC(=O)c1cc2c(cn1)[nH]c3ccccc23

InChI

1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)

InChI key

QMCOPDWHWYSJSA-UHFFFAOYSA-N

Gene Information

human ... BZRAP1(9256)

说明

Biochem/physiol Actions

Benzodiazepine inverse receptor agonist; potent anxiogenic agent.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Solutions may be stored for several days at 4 °C.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Memory enhancement with event-related stimulation of the rostral intralaminar thalamic nuclei.

Robert G Mair et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(52), 14293-14300 (2008-12-26)

The rostral intralaminar thalamic nuclei (ILn) are organized to activate pathways originating in medial prefrontal cortex (mPF) that mediate memory-guided responding during alert, wakeful states. Previous studies have shown that rostral ILn or mPF lesions produce deficits in delayed matching

The autonomic stress-induced hyperthermia response is not enhanced by several anxiogenic drugs.

Lotte C Houtepen et al.

Physiology & behavior, 102(1), 105-109 (2010-09-11)

While anxiety models are often based on locomotor activity responses, the stress-induced hyperthermia (SIH) paradigm uses the autonomic stress response by measuring body temperature. The effects of putative anxiogenic compounds in the SIH paradigm are inconclusive in mice and have

Post-weaning social isolation attenuates c-Fos expression in GABAergic interneurons in the basolateral amygdala of adult female rats.

Jodi L Lukkes et al.

Physiology & behavior, 107(5), 719-725 (2012-05-16)

Previous studies have found that adolescent social isolation of rats can lead to an increased anxiety state during adulthood, while chronic anxiety states are associated with dysregulated local GABAergic inhibition within the basolateral amygdala (BL). Therefore, we investigated the effects

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全球贸易项目编号

货号	GTIN
E006-100MG	04061832556413
E006-500MG	04061832556420