D9503
3,4-二羟基- DL- 苯丙氨酸
别名:
3-（3,4-二羟基苯基）-DL丙氨酸, DL-3-羟基酪氨酸, DL-DOPA
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关于此项目
线性分子式:
(HO)2C6H3CH2CH(NH2)COOH
化学文摘社编号:
分子量:
197.19
NACRES:
NA.32
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-566-0
MDL number:
Beilstein/REAXYS Number:
3204800
Quality Level
InChI key
WTDRDQBEARUVNC-UHFFFAOYSA-N
InChI
1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)
SMILES string
NC(Cc1ccc(O)c(O)c1)C(O)=O
form
powder
mp
270-272 °C (lit.)
290 °C (dec.) (lit.)
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
mouse ... DRD1(13488), DRD2(13489), DRD3(13490), DRD4(13491), DRD5(13492)
rat ... DRD1(24316), DRD2(24318), DRD3(29238), DRD4(25432), DRD5(25195)
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Biochem/physiol Actions
3,4-二羟基苯丙氨酸是多巴胺的直接前体，多巴胺是酪氨酸羟化酶的产物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Handbook of Developmental Cognitive Neuroscience (2001)
Dopamine formation, from its immediate precursor 3, 4-dihydroxyphenylalanine, along the rat digestive tract
Vieira-Coelho MA and Soares-da-Silva P
Fundamental & Clinical Pharmacology, 7(5), 235-243 (1993)
Luis García-Fernández et al.
Advanced materials (Deerfield Beach, Fla.), 25(4), 529-533 (2012-11-10)
Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide.
Euitae Kim et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 33(6), 914-920 (2013-03-15)
We validated the use of a novel image-based method for partial volume correction (PVC), structural-functional synergistic resolution recovery (SFS-RR) for the accurate quantification of dopamine synthesis capacity measured using [(18)F]DOPA positron emission tomography. The bias and reliability of SFS-RR were
Steven L Saville et al.
Nanoscale, 5(5), 2152-2163 (2013-02-08)
It has been recently reported that for some suspensions of magnetic nanoparticles the transverse proton relaxation rate, R(2), is dependent on the time that the sample is exposed to an applied magnetic field. This time dependence has been linked to
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