生物来源
synthetic (organic)
质量水平
产品线
BioReagent
检测方案
≥99% (HPLC)
形式
powder
技术
cell culture | mammalian: suitable
溶解性
H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
2-8°C
SMILES字符串
[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
InChI
1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChI key
OLXZPDWKRNYJJZ-RRKCRQDMSA-N
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应用
2′-脱氧腺苷一水合物可作为核苷酸前体用于：
- 在复制与有丝分裂之间的界面上研究同源重组的重要性
- 分析脱氧核苷辅助的转导
- 研究脱氧胞苷的增加对胰腺癌细胞吉西他滨耐药的影响
2′-脱氧腺苷一水合物已被用于制备脱氧核糖核苷储液，用于厌氧培养莫海威芽孢杆菌（ Bacillus mojavensis）菌株，包括JF-2和两个枯草芽孢杆菌（ Bacillus subtilis）菌株。
生化/生理作用
过量的2′-脱氧腺苷转化为三磷酸腺苷（dATP），其可抑制核糖核苷酸还原酶。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
Wilhelm T, et al.
Proceedings of the National Academy of Sciences of the USA, 111(2), 763-768 (2014)
Anaerobic growth of Bacillus mojavensis and Bacillus subtilis requires deoxyribonucleosides or DNA
Folmsbee MJ, et al.
Applied and Environmental Microbiology, 70(9) (2004)
Detection and visualization of protein interactions with protein fragment complementation assays.
I Remy et al.
Methods in molecular biology (Clifton, N.J.), 185, 447-459 (2002-01-05)
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