推荐产品
表单
powder
质量水平
溶解性
H2O: 50 mg/mL
储存温度
2-8°C
SMILES字符串
CS(O)(=O)=O.CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3
InChI
1S/C19H26Cl2N2O.CH4O3S/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;1-5(2,3)4/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H3,(H,2,3,4)/t17-,18-;/m1./s1
InChI key
OJPHNZCUXUUVKU-JAXOOIEVSA-N
基因信息
human ... OPRK1(4986)
应用
(±)-反式-U-50488 甲磺酸盐已被用作 κ -阿片受体的对照激动剂。
生化/生理作用
选择性 κ-已知阿片受体激动剂 (±)-反式-U-50488 甲磺酸盐可诱导利尿。研究发现 U-50488H 与其联合给药时可预防吗啡耐受。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种:
分析证书(COA)
Opioid receptor delta as a global modulator of skin differentiation and barrier function repair
International Journal of Cosmetic Science, 37(4), 386-394 (2015)
Evidence-based complementary and alternative medicine : eCAM, 2022, 2868135-2868135 (2022-08-30)
Acute lung injury (ALI) is one of the common and severe complications of cardiopulmonary bypass (CPB), which is the primary cause of death in intensive care units. Nevertheless, there is a lack of effective treatment for ALI secondary to CPB.
Journal of molecular and cellular cardiology, 31(10), 1809-1819 (1999-10-20)
During myocardial ischaemia the beta-adrenoceptor is activated, which contributes, at least partly, to cardiac arrhythmias via inducing [Ca2+]i oscillations. Since beta-adrenoceptor is negatively modulated by the kappa-opioid receptor in the heart, the present study attempted to determine if kappa-opioid receptor
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain
Journal of Pharmacology and Experimental Therapeutics, 321(3), 1208-1225 (2007)
Psychopharmacology, 237(12), 3715-3728 (2020-09-08)
Major depressive disorder is a leading cause of disability worldwide and is likely precipitated by chronic stress. Although many antidepressants are currently available, these drugs require weeks to months of daily administration before reduction of symptoms occurs and many patients
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