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Merck
CN

D8040

Sigma-Aldrich

反式 -U-50488 甲磺酸盐

别名:

-(±)-3,4-二氯-N-甲基-N- [2-(1-吡咯烷基)环己基] 苯乙酰胺 甲磺酸盐, U-50488H

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About This Item

经验公式(希尔记法):
C19H26Cl2N2O · CH4O3S
分子量:
465.43
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.77

表单

powder

质量水平

溶解性

H2O: 50 mg/mL

储存温度

2-8°C

SMILES字符串

CS(O)(=O)=O.CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3

InChI

1S/C19H26Cl2N2O.CH4O3S/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;1-5(2,3)4/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H3,(H,2,3,4)/t17-,18-;/m1./s1

InChI key

OJPHNZCUXUUVKU-JAXOOIEVSA-N

基因信息

human ... OPRK1(4986)

应用

(±)-反式-U-50488 甲磺酸盐已被用作 κ -阿片受体的对照激动剂。

生化/生理作用

选择性 κ-已知阿片受体激动剂 (±)-反式-U-50488 甲磺酸盐可诱导利尿。研究发现 U-50488H 与其联合给药时可预防吗啡耐受。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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