推荐产品
生物来源
bacterial (Leuconostoc mesenteroides)
质量水平
表单
powder
旋光性
[α]/D 199°
分子量
average mol wt 48,000-90,000
颜色
white
溶解性
H2O: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
SMILES字符串
O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
InChI key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
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应用
右旋糖酐在许多应用中用作血小板聚集剂、血浆增容剂、渗透压调节剂、稳定剂、器官分离介质、基质成分、共聚物、微载体、结合剂、粘度调节剂、抗血栓药、润滑剂和物理结构成分。它们可用作长的亲水性间隔臂，以改善结合/结合蛋白的性能（自由活动）。右旋糖酐可衍生化用于生物传感器系统。
小于 60,000 Da 的右旋糖酐通常被认为是低分子量右旋糖酐。与高分子量右旋糖酐相比，低分子量右旋糖酐由于其粘度、聚集性和渗透性通常更受青睐。高分子量、水溶性、葡聚糖聚合物已被广泛应用于生物医学领域。右旋糖酐 (48,000-90,000) 可用于诱导血液聚集和作为粘度血浆扩张剂 (HVPE)。
小于 60,000 Da 的右旋糖酐通常被认为是低分子量右旋糖酐。与高分子量右旋糖酐相比，低分子量右旋糖酐由于其粘度、聚集性和渗透性通常更受青睐。高分子量、水溶性、葡聚糖聚合物已被广泛应用于生物医学领域。右旋糖酐 (48,000-90,000) 可用于诱导血液聚集和作为粘度血浆扩张剂 (HVPE)。
将右旋糖酐用作长的亲水性间隔臂提高了作用于大分子的固定化蛋白质的性能。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Leena Pitkänen et al.
Investigative ophthalmology & visual science, 46(2), 641-646 (2005-01-27)
To determine the effects of solute molecular weight and lipophilicity on the permeability of a retinal pigment epithelium (RPE)-choroid preparation. Fresh RPE-choroid specimens from bovine eyes were placed in diffusion chambers for permeability experiments with carboxyfluorescein, fluorescein isothiocyanate (FITC)-labeled dextrans
Sahitya Katikaneni et al.
Bioanalysis, 3(21), 2419-2426 (2011-11-15)
The purpose of this study was to optimize parameters pertaining to microdialysis technique so as to make this method feasible for evaluating transdermal transport of macromolecules. Microdialysis experiments were performed in vivo using hairless rats with daniplestim as the model
Andreas M A O Pollet et al.
Micromachines, 11(1) (2020-01-08)
The vasculature plays a central role as the highway of the body, through which nutrients and oxygen as well as biochemical factors and signals are distributed by blood flow. Therefore, understanding the flow and distribution of particles inside the vasculature
Diego Delgado et al.
Human gene therapy, 23(4), 345-355 (2012-02-03)
The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile retinoschisis (XLRS). Vectors were prepared with SLN
Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone).
Van Eerdenbrugh B, Taylor LS.
Pharmaceut. Res., doi: 10-doi: 10 (2012)
实验方案
相关内容
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
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