D2773
地蒽酚
≥90% (HPLC)
别名:
1,8,9-蒽三酚, 1,8-二羟基蒽-9(10H)-酮, 二羟蒽酚, 蒽林
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关于此项目
经验公式（希尔记法）:
C14H10O3
化学文摘社编号:
分子量:
226.23
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
214-538-0
Beilstein/REAXYS Number:
2054360
MDL number:
产品名称
地蒽酚, ≥90% (HPLC)
InChI key
NUZWLKWWNNJHPT-UHFFFAOYSA-N
InChI
1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
SMILES string
Oc1cccc2Cc3cccc(O)c3C(=O)c12
assay
≥90% (HPLC)
form
solid
mp
178-181 °C (lit.)
solubility
chloroform: 20 mg/mL, clear to very slightly hazy, yellow
Quality Level
Gene Information
mouse ... Alox12(11684)
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Alison McGill et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(8), 1012-1014 (2005-04-02)
Anthralin is a potent topical drug, inducing clearance of psoriatic plaques. Anthralin disrupts mitochondrial function and structure, but its mechanism of action remains undefined. This study aimed to determine whether anthralin induced keratinocyte apoptosis as well as to investigate molecular
Wing Man Lau et al.
Pharmaceutics, 5(2), 232-245 (2013-12-05)
Psoriasis is a common, chronic and relapsing inflammatory skin disease. It affects approximately 2% of the western population and has no cure. Combination therapy for psoriasis often proves more efficacious and better tolerated than monotherapy with a single drug. Combination
Iyad Hailat et al.
Rapid communications in mass spectrometry : RCM, 28(2), 149-158 (2013-12-18)
Free sterols are neutral molecules that are difficult to analyze by MALDI or ESI and their molecular ions easily fragment. In order to increase their ionization efficiency and selectivity, sterols were derivatized by different reagents. Selected sterols were converted into
G C Hsieh et al.
Toxicology and applied pharmacology, 107(1), 16-26 (1991-01-01)
Primary cultured rat epidermal keratinocytes were used as an experimental model to detect oxidant-mediated adverse effects of dithranol (anthralin), a widely used antipsoriasis drug with tumor-promoting and skin-irritating properties. Keratinocytes were isolated and prepared from the skin of neonatal rats
C Ronpirin et al.
Genetics and molecular research : GMR, 11(1), 412-420 (2012-03-01)
Although the precise causes of psoriasis remain to be elucidated, psoriasis has been known as a disorder in which factors in the immune system, enzymes and other biochemical substances that regulate skin cell division are functionally imbalanced, thereby resulting in
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