Quality Level
assay
≥97% (HPLC)
form
solution
availability
not available in Japan
concentration
5 mM in DMSO
shipped in
wet ice
storage temp.
−20°C
General description
4,5-二氨基荧光素二乙酸酯(DAF-2 DA)溶液是可检测活细胞中一氧化氮(NO)的膜透过性荧光探针。它可用于研究牛主动脉内皮细胞(BAEC)中的NO合成。DAF-2 DA成像表明，纤毛上皮细胞比非上皮炎性细胞产生更多的NO。
Application
活细胞一氧化氮的细胞可透过性荧光检测剂。
Legal Information
DAF-2 由 Daiichi Pure Chemicals Co.,LTD. 生产。
美国专利号5,874,590
美国专利号5,874,590
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
商品
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
Determinants of shear stress-stimulated endothelial nitric oxide production assessed in real-time by 4, 5-diaminofluorescein fluorescence
Qiu W, et al.
Biochemical and Biophysical Research Communications, 286(2), 328-335 (2001)
Increased nitric oxide production in nasal epithelial cells from allergic patients-RT-PCR analysis and direct imaging by a fluorescence indicator: DAF-2 DA
Takeno S, et al.
Clinical and Experimental Allergy, 31(6), 881-888 (2001)
Rachel A Battaglia et al.
eLife, 8 (2019-11-05)
Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking different mutations to disease-relevant phenotypes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D225-1MG | 04061833562017 |