登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式(希尔记法):
C23H22N4O
化学文摘社编号:
分子量:
370.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
产品名称
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC)
InChI key
FMETVQKSDIOGPX-UHFFFAOYSA-N
SMILES string
Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C5CCCC5
InChI
1S/C23H22N4O/c24-22-21-20(14-27(17-6-4-5-7-17)23(21)26-15-25-22)16-10-12-19(13-11-16)28-18-8-2-1-3-9-18/h1-3,8-15,17H,4-7H2,(H2,24,25,26)
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: soluble 17 mg/mL at ≤60 °C
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
A potent and selective pyrrolo[2,3-d]pyrimidine Lck inhibitor.
Potent and selective inhibitor of Lck, a src family tyrosine kinase.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jorge Luis Galeano Niño et al.
Journal of cell science, 133(5) (2020-02-12)
It has become increasingly evident that T cell functions are subject to translational control in addition to transcriptional regulation. Here, by using live imaging of CD8+ T cells isolated from the Lifeact-EGFP mouse, we show that T cells exhibit a
Susana Rosa et al.
Current protocols in stem cell biology, 50(1), e93-e93 (2019-09-04)
This article describes a screening platform to identify compounds that affect human embryonic vascular development. The procedure comprises the generation of human embryonic-like endothelial cells (ECs) from human pluripotent stem cells (hPSCs) and subsequent maturation under arterial flow conditions; the
Bebhinn Treanor et al.
The Journal of cell biology, 174(1), 153-161 (2006-06-28)
We report the supramolecular organization of killer Ig-like receptor (KIR) phosphorylation using a technique applicable to imaging phosphorylation of any green fluorescent protein-tagged receptor at an intercellular contact or immune synapse. Specifically, we use fluorescence lifetime imaging (FLIM) to report
商品
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持