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经验公式(希尔记法):
C12H18Cl2N2O · HCl
化学文摘社编号:
分子量:
313.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
244-643-7
MDL number:
产品名称
克仑特罗 盐酸盐, ≥95%
InChI
1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
InChI key
OPXKTCUYRHXSBK-UHFFFAOYSA-N
SMILES string
Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
assay
≥95%
form
powder
drug control
Home Office Schedule 4.2
storage temp.
2-8°C
Quality Level
Gene Information
human ... ADRB2(154)
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Application
盐酸克伦特罗已被用作:
- 来自鸡骨骼肌的 β-肾上腺素能受体(β -AR)的激动剂,以诱导大鼠
- 的咬肌、二腹肌和颞肌中的肥大效应。
- 作为串联质谱(MS-MS)中的参照β-激动剂标准
Biochem/physiol Actions
盐酸克伦特罗是一种& # 946;2-肾上腺素受体激动剂和支气管扩张剂。它能有效改善哮喘患者的呼气峰流速(PEFR)。克伦特罗也是一种提高性能的药物,因为它刺激中枢神经系统并改善氧转运。克伦特罗在扩张型心肌病患者中引发心脏保护功能。
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Repr. 1B
法规信息
兴奋剂蛋白同化制剂
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