推荐产品
产品名称
克仑特罗 盐酸盐, ≥95%
质量水平
方案
≥95%
表单
powder
drug control
Home Office Schedule 4.2
储存温度
2-8°C
SMILES字符串
Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
InChI
1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
InChI key
OPXKTCUYRHXSBK-UHFFFAOYSA-N
基因信息
human ... ADRB2(154)
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应用
盐酸克伦特罗已被用作：
- 来自鸡骨骼肌的 β-肾上腺素能受体（＆＃946; -AR）的激动剂，以诱导大鼠
- 的咬肌、二腹肌和颞肌中的肥大效应。
- 作为串联质谱（MS-MS）中的参照β-激动剂标准
生化/生理作用
盐酸克伦特罗是一种& # 946；2-肾上腺素受体激动剂和支气管扩张剂。它能有效改善哮喘患者的呼气峰流速（PEFR）。克伦特罗也是一种提高性能的药物，因为它刺激中枢神经系统并改善氧转运。克伦特罗在扩张型心肌病患者中引发心脏保护功能。
应用
产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Carc. 2 - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
A trial of clenbuterol in bronchial asthma.
Anderson G and Wilkins E
Thorax, 32(6), 717-719 (1977)
C A Izeboud et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 48(9), 497-502 (1999-10-16)
To investigate the suppressive effects of the beta-agonist clenbuterol on the release of TNF-alpha and IL-6 in a lipopolysaccharide (LPS)-model of inflammation, both in vitro and in vivo. Human U-937 cell line (monocyte-derived macrophages), and male Wistar rats (200-250 g).
Jelka Pleadin et al.
Meat science, 86(3), 733-737 (2010-07-30)
The aim of this study was to determine the level of clenbuterol residues in muscle tissue of pigs after repeat administration in a growth-promoting dose. An anabolic dose of clenbuterol (20 μg/kg body mass per day) was administered orally to
I Semkova et al.
Brain research. Brain research reviews, 30(2), 176-188 (1999-10-19)
Neurotrophins and other neurotrophic factors have been shown to support the survival and differentiation of many neuronal populations of the central and peripheral nervous system. Therefore, administering neurotrophic factors could represent an alternative strategy for the treatment of acute and
beta1-and beta2-adrenergic receptor stimulation differ in their effects on PGC-1alpha and atrogin-1/MAFbx gene expression in chick skeletal muscle
Shimamoto S, et al.
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 211, 1-6 (2017)
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