推荐产品
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
CY-A1, monoclonal
分子量
antigen 60 kDa
包含
15 mM sodium azide
种属反应性
mouse, human, monkey, bovine
技术
immunocytochemistry: suitable
microarray: suitable
western blot: 1:1,000 using a mouse NIH 3T3 cell extract
同位素/亚型
IgG2a
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CCNA2(890)
mouse ... Ccna2(12428)
一般描述
细胞周期蛋白 A 是 S 期的核蛋白，它与 cdk2 和 cdc2 结合。与细胞周期蛋白 A 特异性反应的单克隆抗体的可用性使得细胞周期蛋白 A 的亚细胞检测和定位，以及细胞周期蛋白水平的相对差异（作为细胞周期阶段的功能）的测量成为可能。
特异性
该抗体识别牛细胞周期蛋白 A 氨基酸 162-433 中存在的表位。未发现与其他细胞周期蛋白（细胞周期蛋白 B、D 或 E）有交叉反应。
免疫原
重组牛细胞周期蛋白 A。
应用
小鼠单克隆抗 Cyclin A 抗体适用于：
- 免疫细胞化学
- 微阵列
- 蛋白质印迹（使用小鼠 NIH 3T3 细胞提取物，1：1,000 稀释）
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Matthew Hoare et al.
Nature cell biology, 18(9), 979-992 (2016-08-16)
Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse secretome, which provides complex functionality for senescent cells within the tissue microenvironment. We show that oncogene-induced senescence is accompanied by a dynamic fluctuation of NOTCH1 activity, which
Emma L Hesketh et al.
Cell cycle (Georgetown, Tex.), 14(3), 333-341 (2015-02-07)
The minichromosome maintenance complex (MCM2-7) is the putative DNA helicase in eukaryotes, and essential for DNA replication. By applying serial extractions to mammalian cells synchronized by release from quiescence, we reveal dynamic changes to the sub-nuclear compartmentalization of MCM2 as
J E Dazard et al.
Oncogene, 19(33), 3693-3705 (2000-08-19)
p53 transcription factor is mutated in most skin cell carcinomas and in more than 50% of all human malignancies. One of its transcriptional targets is MDM2, which in turn down-regulates p53. The role of the p53/MDM2 regulatory loop upon genotoxic
Qing-Hua Zhang et al.
The Journal of cell biology, 216(10), 3133-3143 (2017-08-19)
Cyclin A2 is a crucial mitotic Cdk regulatory partner that coordinates entry into mitosis and is then destroyed in prometaphase within minutes of nuclear envelope breakdown. The role of cyclin A2 in female meiosis and its dynamics during the transition
Chunyan Weng et al.
International journal of oncology, 42(1), 327-337 (2012-11-09)
Androgen deprivation therapy of prostate cancer with estrogens shows significant cardiovascular side-effects. To develop effective prostate cancer therapeutic agent(s) with minimal cardiovascular side-effects, we compared the effects of various estrogen receptor (ER) ligands on the modulation of dihydrotestosterone (DHT) actions
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